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DWORF Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS541444

FITC-Conjugated Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF AntibodyEnhances the activity of ATP2A1/SERCA1 ATPase in sarcoplasmic reticulum by displacing ATP2A1/SERCA1 inhibitors, thereby acting as a key regulator of skeletal muscle… More details

$610 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DWORF, Polyclonal Antibody
Full Product Name
DWORF Antibody FITC-Conjugated
Product Gene Name
Product Synonym Names
Dwarf open reading frame; DWORF; Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF; SERCA regulator DWORF antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse
Form/Format
FITC-Conjugated
Concentration
0.5 ug/ul in antibody stabilization buffer (lot specific)
Preparation and Storage
-20 degree C for long term storage
Matching Pairs
Antibody: DWORF (MBS541444)
Positive Control: DWORF (MBS542714)
Antibody/Peptide Pairs
DWORF peptide (MBS543604) is used for blocking the activity of DWORF antibody (MBS541444)
Molecular Weight
3,815 Da
3D Structure
ModBase 3D Structure for P0DN83
Immunogen
Synthetic peptide taken within amino acid reigon 1-30 on mouse Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF protein.
Immunoglobulin
IgG
Expression
Highly expressed in heart (at protein level). Detected in heart and soleus, a postural muscle group of the hindlimb containing the highest enrichment of slow-twitch muscle fibers. Also expressed in diaphragm, which contains some slow-twitch fibers. Not detected in the quadriceps, a fast-twitch muscle group, or in cardiac atrial muscle. Not expressed in the prenatal heart but gradually increases in abundance postnatally.
Subcellular Location
Sarcoplasmic reticulum membrane; Single-pass membrane protein
Applications Tested/Suitable for anti-DWORF antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Application Notes for anti-DWORF antibody
ELISA: 1:10,000
Immunohistochemistry: 1:100
Immunoprecipitation: 1:200
Western Blot: 1:500

Other Notes

Small volumes of anti-DWORF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DWORF purchase

MBS541444 is an antibody targeting DWORF. Also known as DWORF Antibody FITC-Conjugated. Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DWORF. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
UniProt Primary Accession #
NCBI Official Full Name
Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF
UniProt Protein Name
Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF
UniProt Synonym Protein Names
Dwarf open reading frame
UniProt Gene Name
DWORF
UniProt Synonym Gene Names
DWORF
UniProt Entry Name
DWORF_MOUSE

UniProt Comments for DWORF

DWORF: Enhances the activity of ATP2A1/SERCA1 ATPase in sarcoplasmic reticulum by displacing ATP2A1/SERCA1 inhibitors, thereby acting as a key regulator of skeletal muscle activity. Does not directly stimulates SERCA pump activity. Enhances sarcoplasmic reticulum Ca(2+) uptake and myocyte contractility by displacing the SERCA inhibitory peptides sarcolipin (SLN), phospholamban (PLN) and myoregulin (MRLN). {ECO:0000250|UniProtKB:P0DN83}. Interacts with ATP2A1/SERCA1. {ECO:0000250|UniProtKB:P0DN83}

Protein type: Membrane protein, integral
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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