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Glucose-6-Phosphate (G6PC2) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS541656

BIOTIN-Conjugated Glucose-6-phosphoate catalytic 2 AntibodyMay hydrolyze glucose-6-phosphate to glucose in the endoplasmic reticulum. May be responsible for glucose production through glycogenolysis and gluconeogenesis. More details

$610 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Glucose-6-Phosphate (G6pc2), Polyclonal Antibody
Full Product Name
Glucose-6-Phosphate, catalytic subunit Antibody BIOTIN-Conjugated
Product Gene Name
anti-G6pc2 antibody
Product Synonym Names
AW107337; G-6-Pase; g6pc; G6PT; Glucose-6-phosphatase alpha; GSD1; GSD1a; MGC163350; MGC93613; RP23-281C18.19 antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Monkey, Mouse, Rat
Form/Format
BIOTIN-Conjugated
Concentration
0.55-0.65 ug/ul in antibody stabilization buffer (lot specific)
Preparation and Storage
-20 degree C for long term storage
Matching Pairs
Antibody: Glucose-6-Phosphate (MBS541656)
Positive Control: Glucose-6-Phosphate (MBS542781)
Antibody/Peptide Pairs
Glucose-6-Phosphate peptide (MBS543712) is used for blocking the activity of Glucose-6-Phosphate antibody (MBS541656)
Molecular Weight
17,894 Da
3D Structure
ModBase 3D Structure for Q9Z186
Immunogen
Synthetic peptide taken within amino acid region 80-130 on G6PC2 protein, and common in larger variant of glucose 6 phosphatase.
Expression
Specifically expressed in pancreatic islet cells, in particular those of beta-cell origin. Not detected in testis, kidney, muscle, liver, lung, spleen, brain, pituitary, gastric fundus or heart.
Molecular Function
Gluconeogenesis
Structure
Belongs to the glucose-6-phosphatase family.
Subcellular Location
Endoplasmic Reticulum Membrane; Multi-pass membrane protein
Applications Tested/Suitable for anti-G6pc2 antibody
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
Application Notes for anti-G6pc2 antibody
ELISA: 1:10,000
Immunoprecipitation: 1:10,000
Western Blot: 1:500

Other Notes

Small volumes of anti-G6pc2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for G6pc2 purchase

MBS541656 is an antibody targeting G6pc2. Also known as Glucose-6-Phosphate, catalytic subunit Antibody BIOTIN-Conjugated. Reactive in Human, Monkey, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for G6pc2. It may not necessarily be applicable to this product.

NCBI GI #
123236727
NCBI Accession #
CAM24718
UniProt Primary Accession #
Q9Z186
UniProt Secondary Accession #
Q2M2M7; A2AUN2
UniProt Protein Name
Glucose-6-phosphatase 2
UniProt Synonym Protein Names
Islet-specific glucose-6-phosphatase catalytic subunit-related protein
Protein Family
Glucose-6-phosphatase
UniProt Gene Name
G6pc2
UniProt Synonym Gene Names
Igrp; G-6-Pase 2; G6Pase 2
UniProt Entry Name
G6PC2_MOUSE

UniProt Comments for G6pc2

G6PC2: May hydrolyze glucose-6-phosphate to glucose in the endoplasmic reticulum. May be responsible for glucose production through glycogenolysis and gluconeogenesis. Belongs to the glucose-6-phosphatase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Carbohydrate Metabolism - galactose; Phosphatase (non-protein); Carbohydrate Metabolism - glycolysis and gluconeogenesis; Transporter; EC 3.1.3.9; Endoplasmic reticulum; Transporter, SLC family; Membrane protein, multi-pass; Carbohydrate Metabolism - starch and sucrose

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane; integral to membrane; membrane

Molecular Function: glucose-6-phosphatase activity; hydrolase activity

Biological Process: dephosphorylation; gluconeogenesis; glucose 6-phosphate metabolic process; glucose homeostasis; regulation of insulin secretion
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-G6pc2 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >7 publications with G6pc2 and Inflammation
 Carcinoma Antibodies  >2 publications with G6pc2 and Carcinoma
 Necrosis Antibodies  >1 publications with G6pc2 and Necrosis
 Myocardial Infarction Antibodies  >1 publications with G6pc2 and Myocardial Infarction
 Memory Disorders Antibodies  >1 publications with G6pc2 and Memory Disorders
 Lung Diseases Antibodies  >1 publications with G6pc2 and Lung Diseases

Organs/Tissues associated with anti-G6pc2 antibody

 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >58 publications with G6pc2 and Pancreas
 Kidney Antibodies  >5 publications with G6pc2 and Kidney
 Mixed Antibodies  >4 publications with G6pc2 and Mixed
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