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GDF8 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS541679

FITC-Conjugated Myostatin AntibodyActs specifically as a negative regulator of skeletal muscle growth. More details

$610 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GDF8 / Myostatin, Polyclonal Antibody
Full Product Name
GDF8 / Myostatin Antibody FITC
Product Gene Name
Product Synonym Names
GDF 8; Growth differentiation factor 8; MSLHP; MSTN; myostatin antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Rat
Form/Format
FITC-Conjugated
Concentration
0.5 ug/ul in antibody stabilization buffer (lot specific)
Preparation and Storage
-20 degree C for long term storage
Matching Pairs
Antibody/Peptide Pairs
Molecular Weight
42,750 Da
3D Structure
ModBase 3D Structure for Q53S46
Immunogen
Synthetic peptide taken within amino acid region 325-375 on human Myostatin.
Immunoglobulin
IgG
Molecular Function
Cytokine activity; Growth factor activity; heparin binding; identical protein binding; receptor binding; transforming growth factor beta receptor binding
Structure
Homodimer; disulfide-linked (By similarity). Interacts with WFIKKN2, leading to inhibit its activity. Interacts with FST3. Belongs to the TGF-beta family.
Subcellular Location
Secreted; Cytoplasm
Applications Tested/Suitable for anti-GDF8 antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Application Notes for anti-GDF8 antibody
ELISA: 1:10,000
Immunoprecipitation: 1:200
Western Blot: 1:500

Other Notes

Small volumes of anti-GDF8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GDF8 purchase

MBS541679 is an antibody targeting GDF8. Also known as GDF8 / Myostatin Antibody FITC. Reactive in Human, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GDF8. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
myostatin
NCBI Official Synonym Full Names
myostatin
NCBI Official Symbol
MSTN
NCBI Official Synonym Symbols
GDF8; MSLHP
UniProt Protein Name
Growth differentiation factor 8
UniProt Synonym Protein Names
Growth differentiation factor 8
UniProt Gene Name
GDF8
UniProt Entry Name
Q53S46_HUMAN
NCBI Protein Information
growth/differentiation factor 8

NCBI Summary for GDF8

This gene encodes a member of the TGF-beta (transforming growth factor-beta) family of proteins. The encoded preproprotein is proteolytically processed to generate an N-terminal propeptide and a C-terminal subunit. The C-terminal subunits form the mature homodimer, which negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. [provided by RefSeq, Nov 2015]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-GDF8 antibody

 Products by Pathway  Pathway Diagram
 Hypertrophy Model Pathway antibodies  Hypertrophy Model Pathway Diagram
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