• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

JMJD2D Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS541935

FITC-Conjugated Jumonji domain-containing protein 2D AntibodyHistone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4… More details

$610 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
JMJD2D, Polyclonal Antibody
Full Product Name
JMJD2D Antibody FITC-Conjugated
Product Gene Name
anti-JMJD2D antibody
Product Synonym Names
JHD3D; JHDM3D; JmjC domain-containing histone demethylation protein 3D; Jumonji domain-containing protein 2D; Kdm4d; Lysine-specific demethylase 4D antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Monkey
Form/Format
FITC-Conjugated
Concentration
0.55-0.75 ug/ul in antibody stabilization buffer (lot specific)
Preparation and Storage
-20 degree C for long term storage
Matching Pairs
Antibody: JMJD2D (MBS541935)
Positive Control: JMJD2D (MBS542886)
Antibody/Peptide Pairs
JMJD2D peptide (MBS543885) is used for blocking the activity of JMJD2D antibody (MBS541935)
Molecular Weight
58,603 Da
OMIM
609766
3D Structure
ModBase 3D Structure for Q6B0I6
Immunogen
Synthetic peptide taken within amino acid region 340-390 on human Jumonji domain containg 2D protein.
Molecular Function
Chromatin regulator, Dioxygenase, Oxidoreductase
Structure
Belongs to the JHDM3 histone demethylase family.
Contains 1 JmjC domain.
Contains 1 JmjN domain.
Subcellular Location
Nucleus
Applications Tested/Suitable for anti-JMJD2D antibody
ELISA (EIA), IMM, Western Blot (WB)
Application Notes for anti-JMJD2D antibody
Dot Blot: 1:10,000
ELISA: 1:10,000
Immunoprecipitation: 1:150
Western Blot: 1:500

Other Notes

Small volumes of anti-JMJD2D antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for JMJD2D purchase

MBS541935 is an antibody targeting JMJD2D. Also known as JMJD2D Antibody FITC-Conjugated. Reactive in Human, Monkey. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for JMJD2D. It may not necessarily be applicable to this product.

NCBI GI #
111598972
NCBI GeneID
55693
NCBI Accession #
AAI19011.1
UniProt Primary Accession #
Q6B0I6
UniProt Secondary Accession #
Q0VF39; Q9NT41; Q9NW76; B3KPC4
UniProt Related Accession #
Q6B0I6
NCBI Official Full Name
Jumonji domain containing 2D
NCBI Official Synonym Full Names
lysine demethylase 4D
NCBI Official Symbol
KDM4D
NCBI Official Synonym Symbols
JMJD2D
UniProt Protein Name
Lysine-specific demethylase 4D
UniProt Synonym Protein Names
JmjC domain-containing histone demethylation protein 3D; Jumonji domain-containing protein 2D
UniProt Gene Name
KDM4D
UniProt Synonym Gene Names
JHDM3D; JMJD2D
UniProt Entry Name
KDM4D_HUMAN
NCBI Protein Information
lysine-specific demethylase 4D

UniProt Comments for JMJD2D

JMJD2D: Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys- 9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Belongs to the JHDM3 histone demethylase family.

Protein type: Oxidoreductase; EC 1.14.11.-

Chromosomal Location of Human Ortholog: 11q21

Cellular Component: nucleoplasm

Molecular Function: dioxygenase activity; histone demethylase activity; histone demethylase activity (H3-K9 specific); metal ion binding

Biological Process: double-strand break repair via homologous recombination; histone H3-K9 demethylation; regulation of protein amino acid phosphorylation; regulation of transcription, DNA-dependent; transcription, DNA-dependent
Show more

Research Articles on JMJD2D

1. KDM4D-RNA interaction is required for KDM4D accumulation at DNA breakage sites

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-JMJD2D antibody

 Products by Pathway  Pathway Diagram
 Chromatin Modifying Enzymes Pathway antibodies  Chromatin Modifying Enzymes Pathway Diagram
 Chromatin Organization Pathway antibodies  Chromatin Organization Pathway Diagram
 HDMs Demethylate Histones Pathway antibodies  HDMs Demethylate Histones Pathway Diagram

Diseases associated with anti-JMJD2D antibody

 Disease Name  Pubmed Publications
 Neoplasms, Experimental Antibodies  >1 publications with JMJD2D and Neoplasms, Experimental
 Prostatic Diseases Antibodies  >1 publications with JMJD2D and Prostatic Diseases

Organs/Tissues associated with anti-JMJD2D antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >2 publications with JMJD2D and Lung
 Testis Antibodies  >1 publications with JMJD2D and Testis
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000