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LAMP1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS541968

BIOTIN-Conjugated Lysosome-associated membrane glycoprotein 1 AntibodyPresents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis. More details

$610 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LAMP1, Polyclonal Antibody
Full Product Name
LAMP1 Antibody BIOTIN-Conjugated
Product Gene Name
anti-LAMP1 antibody
Product Synonym Names
CD107 antigen like family member A; LAMP 1; LAMPA; LGP120; lgpA; Lysosomal Associated Membrane Protein 1 antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Monkey
Form/Format
BIOTIN-Conjugated
Concentration
0.55-0.75 ug/ul in antibody stabilization buffer (lot specific)
Preparation and Storage
-20 degree C for long term storage
Matching Pairs
Antibody: LAMP1 (MBS541968)
Positive Control: LAMP1 (MBS542907)
Antibody/Peptide Pairs
LAMP1 peptide (MBS543917) is used for blocking the activity of LAMP1 antibody (MBS541968)
Molecular Weight
38,986 Da
OMIM
153330
3D Structure
ModBase 3D Structure for P11279
Immunogen
Synthetic peptide taken within amino acid region 300-350 on human LAMP1 protein.
Molecular Function
Enzyme binding
Subcellular Location
Cell membrane, Single-pass type I membrane protein, endosome membrane, lysosome membrane (Note:This protein shuttles between lysosomes, endosomes, and Plasma membrane. Colocalizes with OSBPL1A at the late endosome)
Applications Tested/Suitable for anti-LAMP1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-LAMP1 antibody
Dot Blot: 1:10,000
ELISA: 1:10,000
Western Blot: 1:500

Other Notes

Small volumes of anti-LAMP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LAMP1 purchase

MBS541968 is an antibody targeting LAMP1. Also known as LAMP1 Antibody BIOTIN-Conjugated. Reactive in Human, Monkey. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LAMP1. It may not necessarily be applicable to this product.

NCBI GI #
206729915
NCBI GeneID
3916
NCBI Accession #
P11279.3
UniProt Primary Accession #
P11279
UniProt Secondary Accession #
Q8WU33; Q96I40; Q9BRD2; Q9NP13; B4DWL3
UniProt Related Accession #
P11279
NCBI Official Full Name
Lysosome-associated membrane glycoprotein 1
NCBI Official Synonym Full Names
lysosomal associated membrane protein 1
NCBI Official Symbol
LAMP1
NCBI Official Synonym Symbols
LAMPA; CD107a; LGP120
UniProt Protein Name
Lysosome-associated membrane glycoprotein 1
UniProt Synonym Protein Names
CD107 antigen-like family member A; CD_antigen: CD107a
Protein Family
Lysosome-associated membrane glycoprotein
UniProt Gene Name
LAMP1
UniProt Synonym Gene Names
LAMP-1; Lysosome-associated membrane protein 1
UniProt Entry Name
LAMP1_HUMAN
NCBI Protein Information
lysosome-associated membrane glycoprotein 1

NCBI Summary for LAMP1

The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq, Jul 2008]

UniProt Comments for LAMP1

LAMP1: Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis. Belongs to the LAMP family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 13q34

Cellular Component: cell soma; cytoplasm; cytosol; dendrite; endosome membrane; external side of plasma membrane; integral to plasma membrane; late endosome; lysosomal membrane; lysosome; melanosome; membrane; multivesicular body; perinuclear region of cytoplasm; plasma membrane; sarcolemma; synaptic vesicle

Molecular Function: enzyme binding; protein binding; protein domain specific binding; viral receptor activity

Biological Process: autophagic cell death; autophagy; entry of virus into host cell; induction of apoptosis by granzyme; positive regulation of natural killer cell degranulation; positive regulation of natural killer cell mediated cytotoxicity; protein stabilization
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Research Articles on LAMP1

1. A unique triad of histidines of Lassa Virus GP1 forms a binding site for host LAMP1.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-LAMP1 antibody

 Reference Product  PubMed Publications
 EEA1 antibody  >45 publications with LAMP1 and EEA1
 CD63 antibody  >38 publications with LAMP1 and CD63
 EGFR antibody  >20 publications with LAMP1 and EGFR
 RAB5A antibody  >8 publications with LAMP1 and RAB5A
 NCAM1 antibody  >4 publications with LAMP1 and NCAM1
 IL21 antibody  >1 publications with LAMP1 and IL21
 RAB7A antibody  >1 publications with LAMP1 and RAB7A

Pathways associated with anti-LAMP1 antibody

 Products by Pathway  Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Senescence And Autophagy Pathway antibodies  Senescence And Autophagy Pathway Diagram
 Tuberculosis Pathway antibodies  Tuberculosis Pathway Diagram
 Tuberculosis Pathway antibodies  Tuberculosis Pathway Diagram

Diseases associated with anti-LAMP1 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >69 publications with LAMP1 and Nervous System Diseases
 Brain Diseases Antibodies  >60 publications with LAMP1 and Brain Diseases
 Disease Models, Animal Antibodies  >54 publications with LAMP1 and Disease Models, Animal
 Inflammation Antibodies  >26 publications with LAMP1 and Inflammation
 Necrosis Antibodies  >25 publications with LAMP1 and Necrosis
 Neoplasms, Experimental Antibodies  >22 publications with LAMP1 and Neoplasms, Experimental
 Lung Diseases Antibodies  >20 publications with LAMP1 and Lung Diseases
 Fibrosis Antibodies  >14 publications with LAMP1 and Fibrosis
 Liver Diseases Antibodies  >13 publications with LAMP1 and Liver Diseases
 Lung Neoplasms Antibodies  >12 publications with LAMP1 and Lung Neoplasms

Organs/Tissues associated with anti-LAMP1 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >137 publications with LAMP1 and Blood
 Brain Antibodies  >84 publications with LAMP1 and Brain
 Bone Antibodies  >38 publications with LAMP1 and Bone
 Liver Antibodies  >37 publications with LAMP1 and Liver
 Lung Antibodies  >37 publications with LAMP1 and Lung
 Nerve Antibodies  >32 publications with LAMP1 and Nerve
 Kidney Antibodies  >31 publications with LAMP1 and Kidney
 Vascular Antibodies  >30 publications with LAMP1 and Vascular
 Heart Antibodies  >29 publications with LAMP1 and Heart
 Muscle Antibodies  >27 publications with LAMP1 and Muscle
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