Mannose Receptor C Type 1 Like Protein 1 (MRC1) ELISA Kit for Cat

Name: Cat MRC1 ELISA Kit; Mannose Receptor C Type 1 Like Protein 1; MyBioSource
Brand: MyBioSource
SKU: MBS054322
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS054322

MBS054322 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Mannose Receptor C Type 1 Like Protein 1 (MRC1) ELISA Kit target analytes in biological samples. The concentration… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Mannose Receptor C Type 1 Like Protein 1 (MRC1), ELISA Kit

Full Product Name

Cat Mannose Receptor C Type 1 Like Protein 1 ELISA Kit

Product Gene Name

MRC1 elisa kit

Species Reactivity

Cat

Preparation and Storage

Store all reagents at 2-8 degree C

Molecular Weight

166,012 Da

OMIM

153618

3D Structure

ModBase 3D Structure for P22897

Other Notes

Small volumes of MRC1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MRC1. It may not necessarily be applicable to this product.

NCBI GI #

4505245

NCBI GeneID

4360

NCBI Accession #

NP_002429.1

UniProt Primary Accession #

P22897

UniProt Secondary Accession #

Q5VSJ2; Q5VSK2; A5PKW3

UniProt Related Accession #

P22897

GenBank Nucleotide #

NM_002438.3

NCBI Official Full Name

macrophage mannose receptor 1

NCBI Official Synonym Full Names

mannose receptor, C type 1

NCBI Official Symbol

MRC1

NCBI Official Synonym Symbols

MMR; CD206; MRC1L1; CLEC13D; CLEC13DL; bA541I19.1

UniProt Protein Name

Macrophage mannose receptor 1

UniProt Synonym Protein Names

C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; Macrophage mannose receptor 1-like protein 1

Protein Family

Macrophage mannose receptor

UniProt Gene Name

MRC1

UniProt Synonym Gene Names

CLEC13D; CLEC13DL; MRC1L1; MMR

UniProt Entry Name

MRC1_HUMAN

NCBI Protein Information

macrophage mannose receptor 1; mannose receptor, C type 1-like 1; C-type lectin domain family 13 member D; macrophage mannose receptor 1-like protein 1

NCBI Summary for MRC1

The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Apr 2011]

UniProt Comments for MRC1

MRC1: Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 10p12.33

Cellular Component: cell surface; integral to plasma membrane; plasma membrane; endosome membrane

Molecular Function: mannose binding; protein binding; transmembrane receptor activity; receptor activity

Biological Process: receptor-mediated endocytosis; signal transduction

Research Articles on MRC1

1. The MRC1/CD68 ratio is positively associated with adipose tissue lipogenesis and with muscle mitochondrial gene expression in humans.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with MRC1 elisa kit

Reference Product	PubMed Publications
CD163 elisa kit	>7 publications with MRC1 and CD163
CHEK2 elisa kit	>3 publications with MRC1 and CHEK2
ITGAM elisa kit	>1 publications with MRC1 and ITGAM

Pathways associated with MRC1 elisa kit

Products by Pathway	Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Antigen Processing-Cross Presentation Pathway antibodies	Antigen Processing-Cross Presentation Pathway Diagram
Class I MHC Mediated Antigen Processing & Presentation Pathway antibodies	Class I MHC Mediated Antigen Processing & Presentation Pathway Diagram
Cross-presentation Of Soluble Exogenous Antigens (endosomes) Pathway antibodies	Cross-presentation Of Soluble Exogenous Antigens (endosomes) Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Phagosome Pathway antibodies	Phagosome Pathway Diagram
Phagosome Pathway antibodies	Phagosome Pathway Diagram
Tuberculosis Pathway antibodies	Tuberculosis Pathway Diagram
Tuberculosis Pathway antibodies	Tuberculosis Pathway Diagram

Diseases associated with MRC1 elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>15 publications with MRC1 and Inflammation
Neoplasms Antibodies	>9 publications with MRC1 and Neoplasms
Lung Diseases Antibodies	>7 publications with MRC1 and Lung Diseases
Necrosis Antibodies	>5 publications with MRC1 and Necrosis
Disease Models, Animal Antibodies	>3 publications with MRC1 and Disease Models, Animal
Weight Loss Antibodies	>3 publications with MRC1 and Weight Loss
Congenital Abnormalities Antibodies	>2 publications with MRC1 and Congenital Abnormalities
Breast Neoplasms Antibodies	>1 publications with MRC1 and Breast Neoplasms
Edema Antibodies	>1 publications with MRC1 and Edema
Cognition Disorders Antibodies	>1 publications with MRC1 and Cognition Disorders

Organs/Tissues associated with MRC1 elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>22 publications with MRC1 and Blood
Muscle Antibodies	>15 publications with MRC1 and Muscle
Brain Antibodies	>7 publications with MRC1 and Brain
Adipose Tissue Antibodies	>6 publications with MRC1 and Adipose Tissue
Liver Antibodies	>4 publications with MRC1 and Liver
Spleen Antibodies	>4 publications with MRC1 and Spleen
Kidney Antibodies	>4 publications with MRC1 and Kidney
Lung Antibodies	>4 publications with MRC1 and Lung
Connective Tissue Antibodies	>3 publications with MRC1 and Connective Tissue
Eye Antibodies	>3 publications with MRC1 and Eye