• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

PDE4B1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS543495

Affinity Purified cAMP-specific phosphodiesterase isoform PDE4B1 AntibodyHydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. More details

$540 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PDE4B1, Polyclonal Antibody
Full Product Name
PDE4B1 Antibody
Product Gene Name
anti-PDE4B1 antibody
Product Synonym Names
5''-cyclic phosphodiesterase 4B; cAMP-specific 3''; cAMP-specific 3', 5'-cyclic phosphodiesterase 4B; cAMP-specific phosphodiesterase-4 B isoform; DKFZp686F2182; DPDE4; dunce-like phosphodiesterase E4; MGC126529; PDE 4B; PDE IVB; PDE32; PDE4B5; Phosphodiesterase 4B; Phosphodiesterase 4B cAMP specific antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Affinity Purified
Concentration
0.60-0.90 ug/ul in antibody stabilization buffer (lot specific)
Preparation and Storage
-20 degree C for long term storage
Matching Pairs
Antibody: PDE4B1 (MBS543495)
Positive Control: PDE4B1 (MBS543081)
Antibody/Peptide Pairs
PDE4B1 peptide (MBS544199) is used for blocking the activity of PDE4B1 antibody (MBS543495)
Molecular Weight
81,737 Da
3D Structure
ModBase 3D Structure for P14646
Immunogen
Synthetic peptide selective only for PDE4B1 subtype variant.
Expression
Widely expressed. Isoform 3 expressed in brain, heart, lung and liver. Isoform 4 expressed in liver and brain.
Molecular Function
Hydrolase, 3', 5'-cyclic-AMP phosphodiesterase activity, cAMP binding

Product Categories/Family for anti-PDE4B1 antibody

Primary Antibodies; Signal Transduction; Second Messengers; cAMP; PDE4B1 Antibody
Applications Tested/Suitable for anti-PDE4B1 antibody
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
Application Notes for anti-PDE4B1 antibody
Dot Blot: 1:10,000
ELISA: 1:10,000
Western Blot: 1:500

Other Notes

Small volumes of anti-PDE4B1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PDE4B1 purchase

MBS543495 is an antibody targeting PDE4B1. Also known as PDE4B1 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PDE4B1. It may not necessarily be applicable to this product.

NCBI GI #
16930143
NCBI Accession #
AAL31763.1
UniProt Primary Accession #
P14646
UniProt Secondary Accession #
Q5RKL0; Q8VD81; Q8VD82
NCBI Official Full Name
cAMP-specific phosphodiesterase isoform PDE4B1
UniProt Protein Name
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
UniProt Synonym Protein Names
DPDE4
UniProt Gene Name
Pde4b
UniProt Entry Name
PDE4B_RAT

UniProt Comments for PDE4B1

PDE4B: a cAMP-specific phosphodiesterase. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents. Inhibited by rolipram. Three alternatively-spliced isoforms have been described.

Protein type: Nucleotide Metabolism - purine; EC 3.1.4.53; Phosphodiesterase

Cellular Component: centrosome; cytoplasm; cytosol; dendritic spine; excitatory synapse; gamma-tubulin complex; membrane; nucleus; perinuclear region of cytoplasm; postsynaptic density; synaptic vesicle; voltage-gated calcium channel complex; Z disc

Molecular Function: 3',5'-cyclic-AMP phosphodiesterase activity; 3',5'-cyclic-nucleotide phosphodiesterase activity; cAMP binding; gamma-tubulin binding; metal ion binding

Biological Process: cAMP catabolic process; leukocyte migration; neutrophil chemotaxis; neutrophil homeostasis; positive regulation of interferon-gamma production; positive regulation of interleukin-2 production; signal transduction; smooth muscle contraction; T cell receptor signaling pathway
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PDE4B1 antibody

 Reference Product  PubMed Publications
 Adcy2 antibody  >1 publications with PDE4B1 and Adcy2
 Adcy7 antibody  >1 publications with PDE4B1 and Adcy7

Diseases associated with anti-PDE4B1 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >47 publications with PDE4B1 and Inflammation
 Schizophrenia Antibodies  >47 publications with PDE4B1 and Schizophrenia
 Necrosis Antibodies  >43 publications with PDE4B1 and Necrosis
 Disease Models, Animal Antibodies  >22 publications with PDE4B1 and Disease Models, Animal
 Nervous System Diseases Antibodies  >19 publications with PDE4B1 and Nervous System Diseases
 Asthma Antibodies  >17 publications with PDE4B1 and Asthma
 Bipolar Disorder Antibodies  >14 publications with PDE4B1 and Bipolar Disorder
 Nausea Antibodies  >7 publications with PDE4B1 and Nausea
 Vomiting Antibodies  >5 publications with PDE4B1 and Vomiting
 Memory Disorders Antibodies  >5 publications with PDE4B1 and Memory Disorders

Organs/Tissues associated with anti-PDE4B1 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >69 publications with PDE4B1 and Brain
 Lung Antibodies  >23 publications with PDE4B1 and Lung
 Heart Antibodies  >14 publications with PDE4B1 and Heart
 Connective Tissue Antibodies  >4 publications with PDE4B1 and Connective Tissue
 Prostate Antibodies  >3 publications with PDE4B1 and Prostate
 Placenta Antibodies  >2 publications with PDE4B1 and Placenta
 Uncharacterized Tissue Antibodies  >1 publications with PDE4B1 and Uncharacterized Tissue
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000