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PDE4D2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS543518

BIOTIN-Conjugated Phosphodiesterase 4D2 AntibodyHydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. More details

$610 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PDE4D2, Polyclonal Antibody
Full Product Name
PDE4D2 Antibody BIOTIN-Conjugated
Product Gene Name
Product Synonym Names
cAMP specific 3', 5' cyclic phosphodiesterase 4D; DKFZp686M11213; cAMP-specific 3''; cyclic AMP phosphodiesterase; DPDE 3; FLJ97311; HSPDE4D; PDE43; PDE4DN2; Phosphodiesterase 4D, cAMP specific (dunce); Phosphodiesterase E3 dunce homolog Drosophila; STRK 1 antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Chicken, Mouse, Rat
Form/Format
BIOTIN-Conjugated
Concentration
0.76 ug/ul in antibody stabilization buffer (lot specific)
Preparation and Storage
-20 degree C for long term storage
Matching Pairs
Antibody: PDE4D2 (MBS543518)
Positive Control: PDE4D2 (MBS543088)
Antibody/Peptide Pairs
PDE4D2 peptide (MBS544207) is used for blocking the activity of PDE4D2 antibody (MBS543518)
Immunogen
Synthetic peptide corresponding to unique amino acid sequence on PDE4D2 variant gene.
Expression
Expressed in colonic epithelial cells (at protein level). Widespread; most abundant in skeletal muscle. Isoform 6 is detected in brain. Isoform 8 is detected in brain, placenta, lung and kidney. Isoform 7 is detected in heart and skeletal muscle.
Molecular Function
Hydrolase, 3', 5'-cyclic-AMP phosphodiesterase activity, cAMP binding
Structure
Homodimer for the long isoforms. Isoforms with truncated N-termini are monomeric. Isoform 3 is part of a ternary complex containing PRKAR2A, PRKAR2B and AKAP9. Interacts with PDE4DIP. Identified in a complex composed of RYR1, PDE4D, PKA, FKBP1A and protein phosphatase 1.
Subcellular Location
Apical cell membrane, Cytoplasm, Membrane
Applications Tested/Suitable for anti-PDE4D2 antibody
ELISA (EIA), IMM, Western Blot (WB)
Application Notes for anti-PDE4D2 antibody
Dot Blot: 1:10,000
ELISA: 1:10,000
Immunoprecipitation: 1:150
Western Blot: 1:500

Other Notes

Small volumes of anti-PDE4D2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PDE4D2 purchase

MBS543518 is an antibody targeting PDE4D2. Also known as PDE4D2 Antibody BIOTIN-Conjugated. Reactive in Chicken, Mouse, Rat. Host: Rabbit.
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