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PDE8A Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS543570

FITC-Conjugated Pan Phosphodiesterase 8A Antibody Mid-RegionHydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP… More details

$610 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PDE8A, Polyclonal Antibody
Full Product Name
PDE8A Antibody FITC-Conjugated
Product Gene Name
Product Synonym Names
5''-cyclic phosphodiesterase 8A; cAMP specific cyclic nucleotide phosphodiesterase 8A; FLJ16150; High affinity cAMP specific and IBMX insensitive 3'5' cyclic phosphodiesterase 8A; HsT19550; PDE 8A; Phosphodiesterase 8A; Weakly similar to 3'5'-cyclic-nucleotide phosphodiesterase antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Bovine, Human, Monkey, Mouse, Rat
Form/Format
FITC-Conjugated
Concentration
0.59 ug/ul in antibody stabilization buffer (lot specific)
Specificity
This antibody will label only PDE8A variants. This antibody will not cross react with other PDE family members.
Preparation and Storage
-20 degree C for long term storage
Antibody/Peptide Pairs
PDE8A peptide (MBS544232) is used for blocking the activity of PDE8A antibody (MBS543570)
Molecular Weight
35,111 Da
3D Structure
ModBase 3D Structure for Q86XV4
Immunogen
Synthetic cyclic peptide from mid-region common to all PDE8A variants.
Expression
Expressed in most tissues except thymus and peripheral blood leukocytes. Highest levels in testis, ovary, small intestine and colon.
Determinant
Mid-Region
Molecular Function
3', 5'-cyclic-AMP phosphodiesterase activity, Hydrolase, Metal-binding
Structure
Belongs to cyclic nucleotide phosphodiesterase family. PDE8B subfamily. Contains 1 PAC (Pas-associated C-terminal) domain. Contains 1 PAS (PER-ARNT-SIM) domain.
Subcellular Location
Cytosol
Applications Tested/Suitable for anti-PDE8A antibody
Confocal Microscopy (CM), ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Application Notes for anti-PDE8A antibody
Confocal Microscopy||1:250
Dot Blot: 1:10,000
ELISA: 1:10,000
Immunocytochemistry: 1:250
Immunofluorescence: 1:250
Immunohistochemistry: 1:250
Immunoprecipitation: 1:250
Western Blot: 1:500-1:2,000

Other Notes

Small volumes of anti-PDE8A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PDE8A purchase

MBS543570 is an antibody targeting PDE8A. Also known as PDE8A Antibody FITC-Conjugated. Reactive in Bovine, Human, Monkey, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PDE8A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
UniProt Primary Accession #
NCBI Official Full Name
PDE8A protein
UniProt Protein Name
PDE8A protein
UniProt Synonym Protein Names
PDE8A protein
UniProt Gene Name
PDE8A
UniProt Entry Name
Q86XV4_HUMAN

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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