Rabbit Anti-PRDM9 Polyclonal Antibody – Cat# MBS544358

PRDM9 Antibody – Rabbit Polyclonal

Name: PRDM9 Antibody; Polyclonal; Rabbit; Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS544358
Price: 480 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS544358

MBS544358 is an antibody targeting PRDM9. Also known as PRDM9 Antibody Affinity Purified. Reactive in Mouse, Rat. Host: Rabbit. Affinity Purified PR-domain containing protein 9, partiaL Antibody More details

$480 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PRDM9, Polyclonal Antibody

Full Product Name

PRDM9 Antibody Affinity Purified

Product Gene Name

anti-PRDM9 antibody

Product Synonym Names

EC 2.1.1.43; Histone lysine N methyltransferase PRDM9; MEISETZ; PFM6; PR domain containing 9; PRDM 9 antibody

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Mouse, Rat

Form/Format

Affinity Purified

Concentration

0.60-0.65 ug/ul in antibody stabilization buffer (lot specific)

Preparation and Storage

-20 degree C for long term storage

Matching Pairs

Antibody: PRDM9 (MBS544358)
Positive Control: PRDM9 (MBS543161)

Antibody/Peptide Pairs

PRDM9 peptide (MBS544321) is used for blocking the activity of PRDM9 antibody (MBS544358)

Molecular Weight

66,227 Da

3D Structure

ModBase 3D Structure for D2K7F0

Immunogen

Synthetic peptide taken within amino acid region 100-150 on PRDM9 protein.

Molecular Function

metal ion binding, nucleic acid binding

Product Categories/Family for anti-PRDM9 antibody

Primary Antibodies; Epigenetics; Chromatin Modifying Enzymes; Methylation; PRDM9 Antibody

Applications Tested/Suitable for anti-PRDM9 antibody

ELISA (EIA), Western Blot (WB)

Application Notes for anti-PRDM9 antibody

Dot Blot: 1:10,000
ELISA: 1:10,000
Western Blot: 1:500

Other Notes

Small volumes of anti-PRDM9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PRDM9. It may not necessarily be applicable to this product.

NCBI GI #

282192965

NCBI GeneID

56979

NCBI Accession #

ADA81885.1

UniProt Primary Accession #

D2K7F0

UniProt Related Accession #

Q9NQV7

NCBI Official Full Name

PR-domain containing protein 9, partial

NCBI Official Synonym Full Names

PR domain 9

NCBI Official Symbol

PRDM9

NCBI Official Synonym Symbols

PFM6; MSBP3; ZNF899; MEISETZ

UniProt Protein Name

PR-domain containing protein 9

UniProt Synonym Protein Names

PR-domain containing protein 9

Protein Family

Histone-lysine N-methyltransferase

UniProt Gene Name

PRDM9

UniProt Entry Name

D2K7F0_HUMAN

NCBI Protein Information

histone-lysine N-methyltransferase PRDM9

NCBI Summary for PRDM9

The protein encoded by this gene is a zinc finger protein with histone methyltransferase activity that catalyzes histone H3 lysine 4 trimethylation (H3K4me3) during meiotic prophase. This protein contains multiple domains, including a Kruppel-associated box (KRAB) domain, an SSX repression domain (SSXRD), a PRD1-BF1 and RIZ homologous region, a subclass of SET (PR/SET) domain, and a tandem array of C2H2 zinc fingers. The zinc finger array recognizes a short sequence motif, leading to local H3K4me3, and meiotic recombination hotspot activity. The observed allelic variation alters the DNA-binding sequence specificity of the protein, resulting in distinct meiotic recombination hotspots amongst individuals and populations. Multiple alternate alleles of this gene have been described. [provided by RefSeq, Jul 2015]

Research Articles on PRDM9

1. PRDM9 protein variants form functional heteromeric complexes which can bind hotspots sequences. When a heteromeric complex binds at a hotspot of one PRDM9 variant, the other PRDM9 variant, which would otherwise not bind, methylates hotspot nucleosomes

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-PRDM9 antibody

Products by Pathway	Pathway Diagram
Cell Cycle Pathway antibodies	Cell Cycle Pathway Diagram
Chromatin Modifying Enzymes Pathway antibodies	Chromatin Modifying Enzymes Pathway Diagram
Chromatin Organization Pathway antibodies	Chromatin Organization Pathway Diagram
Meiosis Pathway antibodies	Meiosis Pathway Diagram
Meiotic Recombination Pathway antibodies	Meiotic Recombination Pathway Diagram
PKMTs Methylate Histone Lysines Pathway antibodies	PKMTs Methylate Histone Lysines Pathway Diagram

Organs/Tissues associated with anti-PRDM9 antibody

Organ/Tissue Name	Pubmed Publications
Testis Antibodies	>7 publications with PRDM9 and Testis