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IP-10 (CXCL10) Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS546100

IP-10 was originally identified as an IFN-gamma-inducible gene in monocytes, fibroblasts and endothelial cells. It has since been shown that IP-10 mRNA is also induced by LPS, IL-1beta, TNF-alpha, IL-12 and viruses. Additional cell types that have been shown… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
IP-10 (CXCL10), Active Protein
Full Product Name
Recombinant Human IP-10 (rHuIP-10/CXCL10)
Product Synonym Names
human IP-10 (CXCL10); Human IP-10/CXCL10
Host
E Coli
Form/Format
Lyophilized from a 0.2mm filtered concentrated (0.5mg/ml) solution in 20mM PB, pH 7.4, 50mM NaCl
Physical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder
Purity/Purification
>97% by SDS-PAGE and HPLC analyses
Preparation and Storage
This lyophilized preparation is stable at 2-8 degree C, but should be kept at -20 degree C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 degree C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 degree C to -70 degree C. Avoid repeated freeze/thaw cycles.
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Molecular Weight Information
8.5 kDa, a single non-glycosylated polypeptide chain containing 72 amino acids.
Biological Activity
Fully biologically active when compared to standard. Determined by its ability to chemoattract human T-Lymphocytes using a concentration range of 10.0-100.0 ng/ml
Endotoxin Level
Less than 1EU/mg of rHuIP-10/CXCL10 as determined by LAL method
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at <-20 degree C. Further dilutions should be made in appropriate buffered solutions.

Other Notes

Small volumes of IP-10 (CXCL10) active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IP-10 (CXCL10) purchase

MBS546100 is an active protein targeting IP-10 (CXCL10). Also known as Recombinant Human IP-10 (rHuIP-10/CXCL10). Host: E Coli.
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