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SDF-1beta (CXCL12) Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS546112

SDF-1á and are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1á and chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
SDF-1beta (CXCL12), Active Protein
Full Product Name
Recombinant Rat SDF-1(rRt SDF-1 beta/CXCL12)
Product Gene Name
SDF-1beta (CXCL12) active protein
Product Synonym Names
rat SDF-1beta (CXCL12); Rat SDF-1 beta/CXCL12; rat SDF-1b (CXCL12)
Sequence
KPVSLSYRCP CRFFESHVAR ANVHLKILN TPNCALQIVA RLKSNNRQVC IDPKLKWIQE YLDKALNKRL KM
Host
E Coli
Form/Format
Lyophilized from a 0.2mm filtered concentrated solution in 20mM PB, pH 7.4, 150mM NaCl.
Physical Appearance: Sterile FilteredWhite lyophilized (freeze-dried) powder.
Purity/Purification
>97% by SDS-PAGE and HPLC analyses.
Preparation and Storage
This lyophilized preparation is stable at 2-8 degree C, but should be kept at -20 degree C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 degree C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 degree C to -70 degree C. Avoid repeated freeze/thaw cycles.
Molecular Weight
8.4 kDa, a single non-glycosylated polypeptide chain containing 72 amino acids.
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Molecular Weight Information
8.3 kDa, a single non-glycosylated polypeptide chain containing 74 amino acids
Biological Activity
Fully biologically active when compared to standard. Determined by its ability to chemoattract human monocytes using a concentration range of 100.0-200.0 ng/ml.
Endotoxin Level
Less than 1EU/mg of rRtSDF-1/CXCL12 as determined by LAL method.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at <=-20 degree C. Further dilutions should be made in appropriate buffered solutions.

Other Notes

Small volumes of SDF-1beta (CXCL12) active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SDF-1beta (CXCL12) purchase

MBS546112 is an active protein targeting SDF-1beta (CXCL12). Also known as Recombinant Rat SDF-1(rRt SDF-1 beta/CXCL12). Host: E Coli.
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