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ErbB3 FRAGMENT Human Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS546146

Betacellulin (BTC) is a member of the EGF family of cytokines that also includes EGF, TGF-a, Amphiregulin, HB-EGF, Epiregulin, Tomoregulin and the Neuregulins. At the amino acid sequence level, human mature BTC protein exhibits 80% identity with mouse BTC… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
ErbB3 Fragment, Active Protein
Full Product Name
Recombinant Human ErbB3 Fragment (rHu ErbB3-f)
Product Synonym Names
ErbB3 Fragment; human ErbB3; Recombinant Human Betacellulin
Host
E Coli
Form/Format
A white, semitransparent suspension, the normal content of each vial is 1 mg of rhErbB3-f, 1mg aluminum hydroxide and small amount of arginine, sodium chloride, sodium phosphate, and potassium phosphate.
Physical Appearance: A white semitransparent sus
Purity/Purification
>95% by SDS-PAGE and HPLC analyses.
Preparation and Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Molecular Weight Information
Approximately 31 kDa. a homodimer, non-glycosylated polypeptide chain containing 2 x 154 amino acids.
Biological Activity
Fully biologically active. Measured by its ability to postpone tumor emerge time of spontaneous breast cancer in FVB/N transgenic mice and inhibit the development of tumor, effectively inhibit the growth of in situ transplanted breast cancer in FVB/N transgenic mice.
Endotoxin Level
Less than 1EU/ug of rHuErbB3-f as determined by LAL method.

Other Notes

Small volumes of ErbB3 Fragment active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ErbB3 Fragment purchase

MBS546146 is an active protein targeting ErbB3 Fragment. Also known as Recombinant Human ErbB3 Fragment (rHu ErbB3-f). Host: E Coli.
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