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Interferon-Beta1b Human Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS546188

Interferon-beta is one of the type I interferons produced by fibroblasts in response to stimulation by live or inactivated virus or by double-stranded RNA. It is a cytokine with antiviral, antiproliferative, and immunomodulating activity. The synthesis of… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Interferon-beta1b, Active Protein
Full Product Name
Recombinant Human Interferon-beta1b (rHu IFN-beta1b)
Product Synonym Names
Interferon-beta1b, humanIFN-beta1b; Human Interferon-beta; Interferon-b1b, humanIFN-b1b; Recombinant Human Interferon-b1b (rHu IFN-b1b); Human Interferon-b
Host
E Coli
Form/Format
Lyophilized from a 0.2mm filtered concentrated solution in PBS, pH 7.4, containing 3% manitol.
Physical Appearance: Sterile FilteredWhite lyophilized (freeze-dried) powder.
Purity/Purification
>96% by SDS-PAGE and HPLC analyses.
Preparation and Storage
This lyophilized preparation is stable at 2-8 degree C, but should be kept at -20 degree C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 degree C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 degree C to -70 degree C. Avoid repeated freeze/thaw cycles.
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Molecular Weight Information
Approximately 18.4 kDa, a single non-glycosylated polypeptide chain containing 165 amino acids.
Biological Activity
Fully biologically active when compared to standard. The specific activity as determined in a viral resistance assay is less then 0.03 ng/ml, corresponding to a specific activity of 4.0 x 107 IU/ mg.
Endotoxin Level
Less than 1EU/ug of rHuIFN-beta1b as determined by LAL method.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at <-20 degree C. Further dilutions should be made in appropriate buffered solutions.

Other Notes

Small volumes of Interferon-beta1b active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Interferon-beta1b purchase

MBS546188 is an active protein targeting Interferon-beta1b. Also known as Recombinant Human Interferon-beta1b (rHu IFN-beta1b). Host: E Coli.
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