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IL18R1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS551167

MBS551167 is an antibody targeting IL18R1. Also known as Mouse IL18R1 Affinity Purified Polyclonal. Reactive in Mouse. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
IL18R1, Polyclonal Antibody
Full Product Name
Mouse IL18R1 Affinity Purified Polyclonal
Product Gene Name
Product Synonym Gene Name
IL-18R
Product Synonym Names
RAA25047; polyclonal; IL18R1; IL-18R1; IL-18R
Clonality
Polyclonal
Isotype
Rabbit IgG
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Sterile filtered PBS pH 7.4 solution and %5 trehalose.
Purity/Purification
Affinity chromatography employing immobilized recombinant Mouse IL18R1 matrix.
Preparation and Storage
This antibody can be stored in working aliquots at 2C - 8C for one month without detectable loss of activity. The antibody is stable for at least 1 year from date of receipt at -20C.


Avoid repeated freeze/thaw cycles.
Molecular Weight
62,304 Da
Chromosome Location
Chromosome: 2; NC_000002.11 (102979093..103015230). Location: 2q12
OMIM
604494
3D Structure
ModBase 3D Structure for Q13478
Host Note
Polyclonal Mouse IL18R1 antibody was produced from sera of rabbits immunized with recombinant Mouse IL18R1
Application Notes for anti-IL18R1 antibody
Western Blot Concentration: 0.1-0.2 ug/ml
Western Blot Limit: 0.5ng/lane
ELISA Concentration: 0.5-1 ug/ml
ELISA Limit: 2 pg/well

Other Notes

Small volumes of anti-IL18R1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IL18R1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
interleukin-18 receptor 1 isoform 2
NCBI Official Synonym Full Names
interleukin 18 receptor 1
NCBI Official Symbol
IL18R1
NCBI Official Synonym Symbols
CD218a; IL18RA; IL1RRP; CDw218a; IL-1Rrp
UniProt Protein Name
Interleukin-18 receptor 1
UniProt Synonym Protein Names
CD218 antigen-like family member A; CDw218a; IL1 receptor-related protein
UniProt Gene Name
IL18R1
UniProt Synonym Gene Names
IL1RRP; IL-18R-1; IL-18R1; IL-1Rrp; IL1R-rp
UniProt Entry Name
IL18R_HUMAN
NCBI Protein Information
interleukin-18 receptor 1; IL-18R1; IL1R-rp; IL-18R-1; cytokine receptor; IL1 receptor-related protein; CD218 antigen-like family member A

NCBI Summary for IL18R1

The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
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UniProt Comments for IL18R1

IL18R1: Receptor for interleukin 18 (IL-18). Binding to the agonist leads to the activation of NF-kappa-B. Belongs to the interleukin-1 receptor family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q12

Cellular Component: integral to membrane; plasma membrane

Molecular Function: protein binding; receptor activity; interleukin-1 receptor activity; interleukin-18 receptor activity

Biological Process: positive regulation of interferon-gamma production; T-helper 1 cell differentiation; natural killer cell activation; immune response; positive regulation of NF-kappaB import into nucleus; signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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