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IL17RD Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS551186

MBS551186 is an antibody targeting IL17RD. Also known as Human IL17RD Affinity Purified Polyclonal. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
IL17RD, Polyclonal Antibody
Full Product Name
Human IL17RD Affinity Purified Polyclonal
Product Gene Name
Product Synonym Names
RAA05253; polyclonal; IL17RD
Clonality
Polyclonal
Isotype
Rabbit IgG
Host
Rabbit
Preparation and Storage
This antibody can be stored in working aliquots at 2C - 8C for one month without detectable loss of activity. The antibody is stable for at least 1 year from date of receipt at -20C.


Avoid repeated freeze/thaw cycles.
Molecular Weight
82,411 Da
Chromosome Location
Chromosome: 3; NC_000003.11 (57124010..57204345, complement). Location: 3p14.3
OMIM
606807
3D Structure
ModBase 3D Structure for Q8NFM7
Application Notes for anti-IL17RD antibody
Western Blot Concentration: 0.1-0.2 ug/ml
Western Blot Limit: 0.5ng/lane
ELISA Concentration: 0.5-1 ug/ml
ELISA Limit: 2 pg/well

Other Notes

Small volumes of anti-IL17RD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IL17RD. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
interleukin-17 receptor D
NCBI Official Synonym Full Names
interleukin 17 receptor D
NCBI Official Symbol
IL17RD
NCBI Official Synonym Symbols
SEF; HH18; IL-17RD; IL17RLM
UniProt Protein Name
Interleukin-17 receptor D
UniProt Synonym Protein Names
IL17Rhom; Interleukin-17 receptor-like protein; Sef homolog
UniProt Gene Name
IL17RD
UniProt Synonym Gene Names
IL17RLM; SEF; IL-17 receptor D; IL-17RD; hSef
UniProt Entry Name
I17RD_HUMAN
NCBI Protein Information
interleukin-17 receptor D; hSef; IL17Rhom; sef homolog; IL-17 receptor D; interleukin-17 receptor-like protein

NCBI Summary for IL17RD

This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. The encoded protein is a component of the interleukin-17 receptor signaling complex, and the interaction between this protein and IL-17R does not require the interleukin (PMID: 19079364). The gene product also affects fibroblast growth factor signaling, inhibiting or stimulating growth through MAPK/ERK signaling (PMID: 21663947, 18096367). [provided by RefSeq, Nov 2011]
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UniProt Comments for IL17RD

IL17RD: Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. May inhibit FGF-induced FGFR1 tyrosine phosphorylation. Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation of ERK. Mediates JNK activation and may be involved in apoptosis. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 3p14.3

Cellular Component: Golgi membrane; nucleoplasm; Golgi apparatus; integral to plasma membrane

Molecular Function: interleukin-17 receptor activity

Biological Process: cytokine and chemokine mediated signaling pathway

Disease: Hypogonadotropic Hypogonadism 18 With Or Without Anosmia
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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