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Hemagglutinin Influenza A-Vietnam 1203-2004-H5N1 (HA H5N1) Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS553127

Influenza A virus subtype H5N1 is a subtype of the Influenza A virus. Subtype H5N1 is commonly known as avian influenzaor bird flu. H5N1 may cause more than one influenza pandemicas it is expected to continue mutating in birds. The dominant strain of HPAI A… More details

$240 / 0.002 mg +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Hemagglutinin Influenza A-Vietnam 1203-2004-H5N1 (HA H5N1), Recombinant Protein
Full Product Name
Hemagglutinin Influenza A-Vietnam 1203-2004-H5N1 Recombinant
Product Gene Name
HA H5N1 recombinant protein
Product Synonym Names
influenza; h5n1; hemagglutinin
Host
Insect Cells (Host protein expression may be lot-specific and can be subject to change during production, including bulk orders)
Form/Format
Lyophilized from PBS pH7.4, 5% trehalose,5% mannitol
Purity/Purification
>90%, as determined by SDS-PAGE and HPLC
Preparation and Storage
The lyophilized protein is stable for at least 2 years from date of receipt at -20 degree C.
Upon reconstitution, this product can be stored in working aliquots at 2 degree - 8 degree C for one month, or at -20 degree C for six months, with a carrier protein without detectable loss of activity.

Avoid repeated freeze/thaw cycles.
Molecular Weight
64,461 Da
3D Structure
ModBase 3D Structure for Q5EP31
Domain
Hemagglutinin
Host Note
DNA sequence encoding Influenza A Virus Hemagglutinin H5N1 subtype Vietnam 1203/2004 strain (Asp17-Gln531), was expressed in Insect cells.
Reconstitution
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers
Molecular Weight Note
Recombinant Influenza H5N1 Hemagglutinin is a disulfide-linked monomer protein, and migrates due to glycosylation as an approximately 70 kDa protein under non-reducing conditions and as 45kDa and 25kDa fragments under reducing conditions in SDS-PAGE.

Product Categories/Family for HA H5N1 recombinant protein

Viral Antigens

Other Notes

Small volumes of HA H5N1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HA H5N1 purchase

MBS553127 is a recombinant protein targeting HA H5N1. Also known as Hemagglutinin Influenza A-Vietnam 1203-2004-H5N1 Recombinant. Host: Insect Cells (Host protein expression may be lot-specific and can be subject to change during production, including bulk orders).

Additional Details

NCBI/Uniprot data below describe general gene information for HA H5N1. It may not necessarily be applicable to this product.

NCBI GI #
82017692
NCBI Accession #
Q5EP31
UniProt Primary Accession #
Q5EP31
NCBI Official Full Name
Hemagglutinin HA
UniProt Protein Name
Hemagglutinin
UniProt Gene Name
HA
UniProt Entry Name
Q5EP31_9INFA

UniProt Comments for HA H5N1

Function: Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore

By similarity. RuleBase RU003324

Subunit structure: Homotrimer of disulfide-linked HA1-HA2

By similarity. RuleBase RU003324 SAAS SAAS008980

Sequence similarities: Belongs to the influenza viruses hemagglutinin family. RuleBase RU003324
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with HA H5N1 recombinant protein

 Reference Product  PubMed Publications
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