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CD150 (SLAM) (CD150) Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS553183

The SLAM family of receptors is a group of type I transmembrane receptors that includes SLAM (CD150; SLAMF1), 2B4 (CD244; SLAMF4), Ly-9 (CD229; SLAMF3), natural killer, T- and B-cell antigen (NTB-A) or Ly108 (in the mouse) (SLAMF6), CD84 (SLAMF5), and… More details

$335 / 0.02 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD150 (SLAM), Recombinant Protein
Full Product Name
Human CD150 Recombinant (SLAM)
Product Gene Name
CD150 recombinant protein
Product Synonym Names
Human CD150 Recombinant (SLAM) ; CD150; CDw150; SLAM; SLAMF1
Host
HEk293 Cells (Host protein expression may be lot-specific and can be subject to change during production, including bulk orders)
Form/Format
Recombinant CD150 is supplied as a 0.2 um filtered PBS solution, pH7.2.
Purity/Purification
>97%, as determined by SDS-PAGE and HPLC
Preparation and Storage
Recombinant SLAM (CD150), as supplied, can be stored in working aliquots at 2 degree - 8 degree C for one month, or at -20 degree C to -70 degree C for twelve months.

Avoid repeated freeze/thaw cycles.
Molecular Weight
37,231 Da
OMIM
603492
3D Structure
ModBase 3D Structure for Q13291
Domain
Ig-like C2
Host Note
Optimized DNA sequence encoding Human extracellular domain of human SLAM (CD150) including a C-terminal 6His tag was expressed in HEK293 cells.
Endotoxin
Endotoxin content was assayed using a LAL gel clot method.
Endotoxin level was found to be less than 0.1 ng/ug (1EU/ug).
Molecular Weight Note
Recombinant SLAM (CD150) is a monomer protein consisting of 228 amino acid residue subunits, due to glycosylation migrates as an approximately 45-50 kDa protein on SDS-PAGE.

Product Categories/Family for CD150 recombinant protein

Receptors CD

Other Notes

Small volumes of CD150 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD150 purchase

MBS553183 is a recombinant protein targeting CD150. Also known as Human CD150 Recombinant (SLAM). Host: HEk293 Cells (Host protein expression may be lot-specific and can be subject to change during production, including bulk orders).

Additional Details

NCBI/Uniprot data below describe general gene information for CD150. It may not necessarily be applicable to this product.

NCBI GI #
4506969
NCBI GeneID
6504
NCBI Accession #
NP_003028.1
UniProt Primary Accession #
Q13291
UniProt Secondary Accession #
Q5W172
UniProt Related Accession #
Q13291; Q96QJ2; Q96QR3; Q9HBE7; Q9HBE8; Q9HBE9
GenBank Nucleotide #
NM_003037.2
NCBI Official Full Name
signaling lymphocytic activation molecule
UniProt Protein Name
Signaling lymphocytic activation molecule
UniProt Synonym Protein Names
CDw150; IPO-3
UniProt Gene Name
SLAMF1
UniProt Synonym Gene Names
SLAM
UniProt Entry Name
SLAF1_HUMAN

UniProt Comments for CD150

SLAM: a type I membrane protein present on the surface of B cells, T cells and CD83+ dendritic cells. A high-affinity self-ligand considered to be important in bidirectional T <-> B-cell stimulation. SLAM-induced signal-transduction events in T lymphocytes are different from those in B cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A (SAP) acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (SHP-2)-dependent signal transduction operates. Its cytoplasmic domain interacts with SAP through part of its SH2 domain, and with SHP-2. Three alternatively spliced isoforms have been described.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 1q23.3

Cellular Component: integral to membrane; phagocytic vesicle; external side of plasma membrane

Molecular Function: protein binding; transmembrane receptor activity; antigen binding

Biological Process: viral reproduction; regulation of catalytic activity; regulation of vesicle fusion; positive regulation of cell proliferation; lymphocyte activation; signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CD150 recombinant protein

 Reference Product  PubMed Publications
 SH2D1A recombinant protein  >4 publications with CD150 and SH2D1A
 FYN recombinant protein  >3 publications with CD150 and FYN
 SH2D1B recombinant protein  >1 publications with CD150 and SH2D1B
 FGR recombinant protein  >1 publications with CD150 and FGR

Pathways associated with CD150 recombinant protein

 Products by Pathway  Pathway Diagram
 Measles Pathway antibodies  Measles Pathway Diagram
 Measles Pathway antibodies  Measles Pathway Diagram

Diseases associated with CD150 recombinant protein

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >2 publications with CD150 and Necrosis

Organs/Tissues associated with CD150 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >15 publications with CD150 and Blood
 Bone Antibodies  >5 publications with CD150 and Bone
 Thymus Antibodies  >5 publications with CD150 and Thymus
 Pharynx Antibodies  >1 publications with CD150 and Pharynx
 Kidney Antibodies  >1 publications with CD150 and Kidney
 Heart Antibodies  >1 publications with CD150 and Heart
 Lymph Node Antibodies  >1 publications with CD150 and Lymph Node
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