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Interleukin-22 (IL-22) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS553228

MBS553228 is a recombinant protein targeting IL-22. Also known as Human Interleukin-22 Recombinant. Host: E Coli (Host protein expression may be lot-specific and can be subject to change during production, including bulk orders). More details

$240 / 0.002 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Interleukin-22 (IL-22), Recombinant Protein
Full Product Name
Human Interleukin-22 Recombinant
Product Gene Name
Product Synonym Names
Human IL-22 Recombinant; ILTIF; ZCYTO18; il22; interleukin-22; il-22
Sequence
KEASLADNNT DVRLIGEKLF HGVSMSERCY LMKQVLNFTL EEVLFPQSDR FQPYMQEVVP FLARLSNRLS TCHIEGDDLH IQRNVQKLKD TVKKLGESGE IKAIGELDLL FMSLRNACI
Host
E Coli (Host protein expression may be lot-specific and can be subject to change during production, including bulk orders)
Form/Format
Recombinant Interleukin-22 was lyophilized from 0.2um filtered concentrated (1.0mg/ml) solution in 500mM NaCl, 20mM Tris, pH 8.0.
Purity/Purification
>95%, as determined by SDS-PAGE and HPLC
Preparation and Storage
Upon reconstitution, this cytokine can be stored in working aliquots at 2 degree - 8 degree C for one month, or at -20 degree C for six months, with a carrier protein without detectable loss of activity.

Avoid repeated freeze/thaw cycles.
Molecular Weight
20,011 Da
OMIM
605330
3D Structure
ModBase 3D Structure for Q9GZX6
Domain
4 Helix Cytokine
Host Note
Optimized DNA sequence encoding Human Interleukin-22 mature chain was expressed in Escherichia Coli.
Endotoxin
Endotoxin content was assayed using a LAL gel clot method.
Endotoxin level was found to be less than 0.1 ng/ug (1EU/ug).
Reconstitution
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Molecular Weight Note
Native human IL-22 has a calculated molecular mass of approximately 17 kDa.

Recombinant IL-22 is a disulfide-linked homodimer protein consisting of 164 amino acid residue subunits, and migrates as an approximately 17 kDa protein under reducing conditions in SDS-PAGE.

Product Categories/Family for IL-22 recombinant protein

Other Notes

Small volumes of IL-22 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IL-22. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
interleukin-22
UniProt Protein Name
Interleukin-22
UniProt Synonym Protein Names
Cytokine Zcyto18; IL-10-related T-cell-derived-inducible factor
UniProt Gene Name
IL22
UniProt Synonym Gene Names
ILTIF; ZCYTO18; IL-22; IL-TIF
UniProt Entry Name
IL22_HUMAN

UniProt Comments for IL-22

IL22: Cytokine that contributes to the inflammatory response in vivo. Belongs to the IL-10 family.

Protein type: Secreted, signal peptide; Cytokine; Secreted

Chromosomal Location of Human Ortholog: 12q15

Cellular Component: extracellular space; extracellular region

Molecular Function: interleukin-22 receptor binding; cytokine activity

Biological Process: cell-cell signaling; response to glucocorticoid stimulus; acute-phase response; inflammatory response
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with IL-22 recombinant protein

 Reference Product  PubMed Publications
 IL10RB recombinant protein  >1 publications with IL-22 and IL10RB

Diseases associated with IL-22 recombinant protein

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >7 publications with IL-22 and Inflammation

Organs/Tissues associated with IL-22 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >13 publications with IL-22 and Blood
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