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CD34 Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS553256

CD34 is a transmembrane glycoprotein expressed by human hematopoietic progenitor cells of lymphoid and myeloid lineage, and various types of colony-forming activity in human bone marrow (BM), cord blood (CB), and mobilized peripheral blood (PB) are contained… More details

$335 / 0.01 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD34, Recombinant Protein
Full Product Name
mouse CD34 Recombinant
Product Gene Name
CD34 recombinant protein
Product Synonym Names
CD34; CD-34
Host
HEk293 Cells (Host protein expression may be lot-specific and can be subject to change during production, including bulk orders)
Form/Format
Recombinant mouse CD34 is supplied as a 0.2 um filtered PBS solution, pH7.2.
Purity/Purification
>95%, as determined by SDS-PAGE and HPLC
Preparation and Storage
The lyophilized protein is stable for at least 2 years from date of receipt at -20 degree C.
Upon reconstitution, this cytokine can be stored in working aliquots at 2 degree - 8 degree C for one month, or at -20 degree C for six months, with a carrier protein without detectable loss of activity.

Avoid repeated freeze/thaw cycles.
Molecular Weight
40,983 Da
3D Structure
ModBase 3D Structure for Q64314
Host Note
Optimized DNA sequence encoding extracellular domain of mouse CD34 including a C-terminal 6His tag was expressed in HEK293 cells.
Endotoxin
Endotoxin content was assayed using a LAL gel clot method.
Endotoxin level was found to be less than 0.1 ng/ug (1EU/ug).
Reconstitution
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers
Molecular Weight Note
Recombinant mouse CD34 is a monomer protein consisting of 270 amino acid residue subunits, due to glycosylation migrates as an approximately 50 kDa protein on SDS-PAGE.

Product Categories/Family for CD34 recombinant protein

Receptors CD

Other Notes

Small volumes of CD34 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD34 purchase

MBS553256 is a recombinant protein targeting CD34. Also known as mouse CD34 Recombinant. Host: HEk293 Cells (Host protein expression may be lot-specific and can be subject to change during production, including bulk orders).

Additional Details

NCBI/Uniprot data below describe general gene information for CD34. It may not necessarily be applicable to this product.

NCBI GI #
19526792
NCBI GeneID
12490
NCBI Accession #
NP_598415.1
UniProt Primary Accession #
Q64314
UniProt Secondary Accession #
Q62550; Q62551
GenBank Nucleotide #
NM_133654.3
NCBI Official Full Name
hematopoietic progenitor cell antigen CD34 isoform 2
UniProt Protein Name
Hematopoietic progenitor cell antigen CD34
Protein Family
Hematopoietic progenitor cell antigen
UniProt Gene Name
Cd34
UniProt Entry Name
CD34_MOUSE

UniProt Comments for CD34

CD34: Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues. Belongs to the CD34 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Cell surface

Cellular Component: intercellular bridge; cell surface; membrane; lysosome; perinuclear region of cytoplasm; apical plasma membrane; cytoplasm; plasma membrane; integral to membrane; basal plasma membrane; extracellular region; external side of plasma membrane

Molecular Function: sulfate binding; carbohydrate binding; transcription factor binding

Biological Process: positive regulation of odontogenesis; negative regulation of nitric oxide biosynthetic process; negative regulation of blood coagulation; negative regulation of tumor necrosis factor production; positive regulation of interleukin-10 production; positive regulation of angiogenesis; cell-cell adhesion; regulation of blood pressure; endothelial cell proliferation; tissue homeostasis; hemopoiesis; cell adhesion; leukocyte migration
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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