• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Il-1 Receptor 1 (CD121a) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS553288

MBS553288 is a recombinant protein targeting CD121a. Also known as Mouse IL-1 receptor 1 Recombinant (CD121a). Host: HEk293 Cells (Host protein expression may be lot-specific and can be subject to change during production, including bulk orders). More details

$335 / 0.02 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IL-1 receptor 1 (CD121a), Recombinant Protein
Full Product Name
Mouse IL-1 receptor 1 Recombinant (CD121a)
Product Gene Name
CD121a recombinant protein
Product Synonym Gene Name
IL-1R1
Product Synonym Names
Mouse CD121a Recombinant (IL1R1) ; CD121A; D2S1473; IL-1R1; IL1R1; IL1RA; P80; IL1R1
Host
HEk293 Cells (Host protein expression may be lot-specific and can be subject to change during production, including bulk orders)
Form/Format
Recombinant Mouse IL-1R (CD121a) is lyophilized from 0.2 um filtered PBS solution, pH7.2, 5% Trehalose.
Purity/Purification
>97%, as determined by SDS-PAGE and HPLC
Preparation and Storage
Recombinant mouse IL-1 receptor type 1 can be stored in working aliquots at 2 degree - 8 degree C for one month, or at -20 degree C to -70 degree C for twelve months.

Avoid repeated freeze/thaw cycles.
Molecular Weight
66,698 Da
3D Structure
ModBase 3D Structure for P13504
Domain
Ig-like C2
Host Note
Optimized DNA sequence encoding Human extracellular domain of mouse IL-1 receptor type 1 including a C-terminal His tag was expressed in HEK293 cells.
Molecular Weight Note
Recombinant IL-R1 (CD121a) is a protein consisting of 330 amino acid residue subunits, due to glycosylation migrates as an approximately 55-60 kDa protein on SDS-PAGE.

Product Categories/Family for CD121a recombinant protein

Receptors CD

Other Notes

Small volumes of CD121a recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CD121a. It may not necessarily be applicable to this product.

NCBI GI #
6680417
NCBI GeneID
16177
NCBI Accession #
NP_032388.1
UniProt Primary Accession #
P13504
GenBank Nucleotide #
NM_008362.2
NCBI Official Full Name
interleukin-1 receptor type 1 isoform 1
UniProt Protein Name
Interleukin-1 receptor type 1
UniProt Synonym Protein Names
CD121 antigen-like family member A; Interleukin-1 receptor alpha; IL-1R-alpha; Interleukin-1 receptor type I; p80
UniProt Gene Name
Il1r1
UniProt Synonym Gene Names
Il-1r1; Il1ra; IL-1R-1; IL-1RT-1; IL-1RT1; IL-1R-alpha; mIL-1R1; mIL-1RI; sIL-1R1; sIL-1RI
UniProt Entry Name
IL1R1_MOUSE

UniProt Comments for CD121a

IL-1RA: Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. Belongs to the interleukin-1 receptor family.

Protein type: EC 2.7.11.25; Membrane protein, integral; Receptor, cytokine

Cellular Component: extracellular space; protein complex; cell surface; membrane; axon; postsynaptic density; plasma membrane; extracellular region; integral to membrane; nucleus

Molecular Function: interleukin-1, Type I, activating receptor activity; ionotropic glutamate receptor binding; signal transducer activity; protein binding; protease binding; platelet-derived growth factor receptor binding; interleukin-1 receptor activity

Biological Process: response to radiation; cytokine and chemokine mediated signaling pathway; regulation of inflammatory response; signal transduction; heat acclimation
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000