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Beta Defensin-2 (BD2) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS553336

Defensins are a large family of peptides of which two groups exist in mammals: alpha defensins and beta defensins, which are distinguishable by the spacing and connectivity of the conserved cysteine residues within the mature peptides.It is thought that… More details

$240 / 0.005 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
beta Defensin-2 (BD2), Recombinant Protein
Full Product Name
Mouse beta Defensin-2 Recombinant
Product Gene Name
Product Synonym Gene Name
BD-2
Product Synonym Names
beta defensin; defb4; bd-2; bd2
Sequence
PEKNPCCKYM K
Host
E Coli (Host protein expression may be lot-specific and can be subject to change during production, including bulk orders)
Form/Format
Recombinant Mouse beta Defensin-2 was lyophilized from 0.2 um filtered 100mM NaCl, 20mM PB, pH 7.4.
Purity/Purification
>98%, as determined by SDS-PAGE and HPLC
Preparation and Storage
The lyophilized protein is stable for at least 2 years from date of receipt at -20 degree C.
Upon reconstitution, this cytokine can be stored in working aliquots at 2 degree - 8 degree C for one month, or at -20 degree C for six months, with a carrier protein without detectable loss of activity.

Avoid repeated freeze/thaw cycles.
Molecular Weight
7,820 Da
3D Structure
ModBase 3D Structure for P82020
Domain
Defensin
Host Note
Optimized DNA sequence encoding Human beta Defensin-2 mature chain was expressed in Escherichia Coli.
Endotoxin
Endotoxin content was assayed using a LAL gel clot method.
Endotoxin level was found to be less than 0.1 ng/ug (1EU/ug).
Reconstitution
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Molecular Weight Note
Native Mouse BD-2 is generated by the proteolytic removal of the signal peptide and propeptide, the molecule has a calculated molecular mass of approximately 6 kDa. Recombinant Mouse beta Defensin-2 is a disulfide-linked monomer protein consisting of 52 amino acid residue subunits, and migrates as an approximately 6 kDa protein under non-reducing and reducing conditions in SDS-PAGE.

Product Categories/Family for BD2 recombinant protein

Other Notes

Small volumes of BD2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BD2 purchase

MBS553336 is a recombinant protein targeting BD2. Also known as Mouse beta Defensin-2 Recombinant. Host: E Coli (Host protein expression may be lot-specific and can be subject to change during production, including bulk orders).

Additional Details

NCBI/Uniprot data below describe general gene information for BD2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
GenBank Nucleotide #
NCBI Official Full Name
beta-defensin 2
UniProt Protein Name
Beta-defensin 2
UniProt Synonym Protein Names
Defensin, beta 2
Protein Family
UniProt Gene Name
Defb2
UniProt Synonym Gene Names
BD-2; mBD-2
UniProt Entry Name
DEFB2_MOUSE

UniProt Comments for BD2

Function: Has bactericidal activity

By similarity.

Subcellular location: Secreted

By similarity.

Tissue specificity: Kidney, uterus and to a lesser extent in heart. Ref.1

Induction: In tracheal epithelium, by lipopolysaccharide or inflammation. Ref.1

Sequence similarities: Belongs to the beta-defensin family.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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