CD1a Antibody

CD1a is a protein of 43 to 49kD expressed on dendritic cells and cortical thymocytes. CD1a antigen expression has been shown to be useful in differentiating Langerhans cells, powerful antigen presenting cells present in skin and epithelia, from interdigitating cells. Immunohistochemical studies for CD1a antigen have reported a reduction in epidermal Langerhans cells in graft versus host disease and the participation of CD1a antigen-positive dendritic cells in atherosclerotic lesion formation and asthmatic inflammation.

Clone MTB1 detects cortical thymocytes, Langerhans cells in epidermis, interdigitating cells of dermis and interdigitating cells of stratified squamous epithelium of tonsil. Clone MTB1 may also detect small focal groups of lymphocytes outside the germinal centers of tonsil indicating a cross-reaction with CD1b antigen

Small volumes of anti-CD1a antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS555085 is an antibody targeting CD1a. Also known as CD1a, Monoclonal Antibody, Mouse. Reactive in Human.