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SEMA3B Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS555103

One family of inhibitory axon guidance molecules is the semaphorins. The semaphorins include secreted, transmembrane, and GPI anchored extracellular molecules that are involved in regulating axon guidance by inhibiting axons from growing toward incorrect… More details

$645 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SEMA3B, Antibody
Full Product Name
SEMA3B, Affinity Purified Antibody, Rabbit
Product Gene Name
Species Reactivity
Bovine, Dog, Human, Mouse, Primate, Rat
Form/Format
Affinity Purified - Liquid
Molecular Weight
83,035 Da
OMIM
601281
Type Info
Rabbit IgG
Immunogen
A synthetic peptide made to an internal portion of the human SEMA 3B protein sequence (between residues 100-200).
Applications Tested/Suitable for anti-SEMA3B antibody
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)

Testing Data of anti-SEMA3B antibody

Image: SEMA3B antibody staining of Neuro-2a cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 594 (red). Protocol on datasheet.
Anti-SEMA3B Antibody – Cat# MBS555103

Testing Data of anti-SEMA3B antibody

Image: Western blot analysis of SEMA3B in A. Hela WCE B. Ntera2 C. A431 D. HepG2 E. MCF7 F. NIH/3T3 G. PC12 H. Cos7. Protocol on datasheet.
Anti-SEMA3B Antibody, Testing Data – Cat# MBS555103

Other Notes

Small volumes of anti-SEMA3B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SEMA3B purchase

MBS555103 is an antibody targeting SEMA3B. Also known as SEMA3B, Affinity Purified Antibody, Rabbit. Reactive in Bovine, Dog, Human, Mouse, Primate, Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for SEMA3B. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
semaphorin-3B isoform 1
NCBI Official Synonym Full Names
semaphorin 3B
NCBI Official Symbol
SEMA3B
NCBI Official Synonym Symbols
SemA; SEMA5; SEMAA; semaV; LUCA-1
UniProt Protein Name
Semaphorin-3B
UniProt Synonym Protein Names
Sema A(V); Semaphorin-V; Sema V
Protein Family
UniProt Gene Name
SEMA3B
UniProt Synonym Gene Names
SEMA5; SEMAA; Sema V
UniProt Entry Name
SEM3B_HUMAN
NCBI Protein Information
semaphorin-3B

NCBI Summary for SEMA3B

The protein encoded by this gene belongs to the class-3 semaphorin/collapsin family, whose members function in growth cone guidance during neuronal development. This family member inhibits axonal extension and has been shown to act as a tumor suppressor by inducing apoptosis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2014]
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UniProt Comments for SEMA3B

SEMA3B: Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. Expressed abundantly but differentially in a variety of neural and nonneural tissues. Belongs to the semaphorin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis; Cell development/differentiation

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: membrane; endoplasmic reticulum

Molecular Function: receptor activity

Biological Process: axon guidance; cell-cell signaling
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-SEMA3B antibody

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