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Musashi (MSI1) Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS555314

Musashi1, a neural RNA-binding protein, plays an important role in regulating cell differentiation in precursor cells. Musashi-1 (Msi-1) has been shown to increase the accumulation of tau isoforms in intracellular inclusions in dementia and Parkinson's. The… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
Musashi (MSI1), Antibody
Full Product Name
Musashi, Affinity Purified, Rabbit
Product Gene Name
anti-MSI1 antibody
Species Reactivity
Human, Mouse, Rat
Form/Format
Affinity Purified - Liquid
Molecular Weight
39,125 Da
OMIM
603328
Type Info
Rabbit IgG
Immunogen
APQPGLASPDSPHDPCK

Product Categories/Family for anti-MSI1 antibody

Antibodies; Stem Cell Research Antibodies; Musashi-1
Applications Tested/Suitable for anti-MSI1 antibody
Immunocytochemistry (ICC), Immunohistochemistry (IHC), Western Blot (WB)

Testing Data of anti-MSI1 antibody

Image: Musashi (green) staining of neural rosettes(human). Nuclei are counterstained blue (DAPI). Image courtesy of Drs. Patricia Wilson and Steve Stice, University of Georgia
Anti-MSI1 Antibody – Cat# MBS555314

Testing Data of anti-MSI1 antibody

Image: Musashi-positive cells in the ventricular zone of E14.5 mouse medulla. Picture was taken at 200x magnification. The sections are 4% PFA fixed, paraffin-embedded and cut at 5 micron. Courtesy of Xi Huang, Chiang Lab, VUMC
Anti-MSI1 Antibody, Testing Data – Cat# MBS555314

Other Notes

Small volumes of anti-MSI1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MSI1 purchase

MBS555314 is an antibody targeting MSI1. Also known as Musashi, Affinity Purified, Rabbit. Reactive in Human, Mouse, Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for MSI1. It may not necessarily be applicable to this product.

NCBI GI #
3786320
NCBI GeneID
4440
NCBI Accession #
BAA33962.1
UniProt Secondary Accession #
Q96PU0; Q96PU1; Q96PU2; Q96PU3
UniProt Related Accession #
O43347
NCBI Official Full Name
Musashi
NCBI Official Synonym Full Names
musashi RNA binding protein 1
NCBI Official Symbol
MSI1
UniProt Protein Name
RNA-binding protein Musashi homolog 1
Protein Family
Chromatin assembly factor
UniProt Gene Name
MSI1
UniProt Synonym Gene Names
Musashi-1
UniProt Entry Name
MSI1H_HUMAN
NCBI Protein Information
RNA-binding protein Musashi homolog 1

UniProt Comments for MSI1

Musashi-1: RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'- GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'- [GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system. Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines. Belongs to the Musashi family.

Protein type: RNA-binding

Chromosomal Location of Human Ortholog: 12q24

Molecular Function: RNA binding

Biological Process: nervous system development
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MSI1 antibody

 Reference Product  PubMed Publications
 NUMB antibody  >16 publications with MSI1 and NUMB
 CDKN1A antibody  >9 publications with MSI1 and CDKN1A

Pathways associated with anti-MSI1 antibody

 Products by Pathway  Pathway Diagram
 MRNA Surveillance Pathway antibodies  MRNA Surveillance Pathway Diagram
 MRNA Surveillance Pathway antibodies  MRNA Surveillance Pathway Diagram

Diseases associated with anti-MSI1 antibody

 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >11 publications with MSI1 and Disease Models, Animal
 Breast Neoplasms Antibodies  >6 publications with MSI1 and Breast Neoplasms
 Liver Diseases Antibodies  >5 publications with MSI1 and Liver Diseases
 Neoplasms, Experimental Antibodies  >5 publications with MSI1 and Neoplasms, Experimental
 Lung Diseases Antibodies  >5 publications with MSI1 and Lung Diseases
 Lung Neoplasms Antibodies  >5 publications with MSI1 and Lung Neoplasms
 Cardiovascular Diseases Antibodies  >5 publications with MSI1 and Cardiovascular Diseases
 Carcinoma, Hepatocellular Antibodies  >4 publications with MSI1 and Carcinoma, Hepatocellular
 Congenital Abnormalities Antibodies  >3 publications with MSI1 and Congenital Abnormalities
 Uterine Cervical Neoplasms Antibodies  >3 publications with MSI1 and Uterine Cervical Neoplasms

Organs/Tissues associated with anti-MSI1 antibody

 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >37 publications with MSI1 and Embryonic Tissue
 Eye Antibodies  >10 publications with MSI1 and Eye
 Testis Antibodies  >7 publications with MSI1 and Testis
 Lung Antibodies  >5 publications with MSI1 and Lung
 Mammary Gland Antibodies  >4 publications with MSI1 and Mammary Gland
 Ovary Antibodies  >3 publications with MSI1 and Ovary
 Pancreas Antibodies  >1 publications with MSI1 and Pancreas
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