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VR1 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS555357

VR1 (vanilloid receptor 1) is a channel activated by capsaicin, the pungent ingredient in hot peppers. It was isolated from sensory neurons. Sequence analysis suggests that VR1 has six transmembrane domains and intracellular N- and C-termini. It shares… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
VR1, Antibody
Full Product Name
VR1- C-Terminus Antiserum, guinea pig
Product Gene Name
anti-VR1 antibody
Species Reactivity
Human, Rat
Form/Format
Whole serum - Liquid
Molecular Weight
94,211 Da
OMIM
602076
3D Structure
ModBase 3D Structure for Q8NER1
Type Info
Guinea Pig IgG
Immunogen
YTGSLKPEDAEVFKDSMVPGEK

Product Categories/Family for anti-VR1 antibody

VR1 C-terminus (TRPV1)
Applications Tested/Suitable for anti-VR1 antibody
Immunohistochemistry (IHC)

Testing Data of anti-VR1 antibody

Anti-VR1 Antibody – Cat# MBS555357

Testing Data of anti-VR1 antibody

Image: TRPV1 staining of mouse inferior olive using Cy3-conjugated donkey anti-rabbit secondary antibodies (red color) and DAPI (blue) as a nuclear counterstain.
Anti-VR1 Antibody, Testing Data – Cat# MBS555357

Other Notes

Small volumes of anti-VR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for VR1 purchase

MBS555357 is an antibody targeting VR1. Also known as VR1- C-Terminus Antiserum, guinea pig. Reactive in Human, Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for VR1. It may not necessarily be applicable to this product.

NCBI GI #
15028819
NCBI GeneID
7442
NCBI Accession #
CAB89866.2
UniProt Primary Accession #
Q8NER1
UniProt Secondary Accession #
Q3LU47; Q9H0G9; Q9H303; Q9H304; Q9NQ74; Q9NY22; A2RUA9
UniProt Related Accession #
Q8NER1
NCBI Official Full Name
vanilloid receptor 1
NCBI Official Synonym Full Names
transient receptor potential cation channel subfamily V member 1
NCBI Official Symbol
TRPV1
NCBI Official Synonym Symbols
VR1
UniProt Protein Name
Transient receptor potential cation channel subfamily V member 1
UniProt Synonym Protein Names
Capsaicin receptor; Osm-9-like TRP channel 1; OTRPC1; Vanilloid receptor 1
UniProt Gene Name
TRPV1
UniProt Synonym Gene Names
VR1; TrpV1; OTRPC1
UniProt Entry Name
TRPV1_HUMAN
NCBI Protein Information
transient receptor potential cation channel subfamily V member 1

UniProt Comments for VR1

TRPV1: a receptor for capsaicin and a non-selective cation channel that is structurally related to members of the TRP family of ion channels. Activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo.

Protein type: Channel, cation; Membrane protein, integral; Membrane protein, multi-pass; Receptor, misc.

Chromosomal Location of Human Ortholog: 17p13.2

Cellular Component: integral to membrane; integral to plasma membrane; intrinsic to plasma membrane; plasma membrane; postsynaptic membrane

Molecular Function: ATP binding; calcium channel activity; calcium-release channel activity; excitatory extracellular ligand-gated ion channel activity; extracellular ligand-gated ion channel activity; phosphoinositide binding; phosphoprotein binding; transmembrane receptor activity

Biological Process: cell surface receptor linked signal transduction; chemosensory behavior; protein homotetramerization; thermoception; transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-VR1 antibody

 Reference Product  PubMed Publications
 TRPA1 antibody  >686 publications with VR1 and TRPA1
 TRPM8 antibody  >351 publications with VR1 and TRPM8
 VR1 antibody  >207 publications with VR1 and VR1
 FOS antibody  >78 publications with VR1 and FOS
 SRC antibody  >14 publications with VR1 and SRC
 CNR1 antibody  >9 publications with VR1 and CNR1
 KCNQ2 antibody  >6 publications with VR1 and KCNQ2
 MMP1 antibody  >5 publications with VR1 and MMP1
 PRKCE antibody  >3 publications with VR1 and PRKCE
 HSF1 antibody  >2 publications with VR1 and HSF1

Pathways associated with anti-VR1 antibody

 Products by Pathway  Pathway Diagram
 Inflammatory Mediator Regulation Of TRP Channels Pathway antibodies  Inflammatory Mediator Regulation Of TRP Channels Pathway Diagram
 Inflammatory Mediator Regulation Of TRP Channels Pathway antibodies  Inflammatory Mediator Regulation Of TRP Channels Pathway Diagram
 Ion Channel Transport Pathway antibodies  Ion Channel Transport Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Stimuli-sensing Channels Pathway antibodies  Stimuli-sensing Channels Pathway Diagram
 TRP Channels Pathway antibodies  TRP Channels Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Trk Receptor Signaling Mediated By PI3K And PLC-gamma Pathway antibodies  Trk Receptor Signaling Mediated By PI3K And PLC-gamma Pathway Diagram
 Trk Receptor Signaling Mediated By The MAPK Pathway antibodies  Trk Receptor Signaling Mediated By The MAPK Pathway Diagram

Diseases associated with anti-VR1 antibody

 Disease Name  Pubmed Publications
 Pain Antibodies  >1832 publications with VR1 and Pain
 Nervous System Diseases Antibodies  >1254 publications with VR1 and Nervous System Diseases
 Inflammation Antibodies  >856 publications with VR1 and Inflammation
 Hyperalgesia Antibodies  >594 publications with VR1 and Hyperalgesia
 Peripheral Nervous System Diseases Antibodies  >177 publications with VR1 and Peripheral Nervous System Diseases
 Necrosis Antibodies  >99 publications with VR1 and Necrosis
 Hypertension Antibodies  >86 publications with VR1 and Hypertension
 Urinary Bladder Diseases Antibodies  >81 publications with VR1 and Urinary Bladder Diseases
 Edema Antibodies  >76 publications with VR1 and Edema
 Heart Diseases Antibodies  >73 publications with VR1 and Heart Diseases

Organs/Tissues associated with anti-VR1 antibody

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >1154 publications with VR1 and Nerve
 Brain Antibodies  >653 publications with VR1 and Brain
 Blood Antibodies  >462 publications with VR1 and Blood
 Skin Antibodies  >382 publications with VR1 and Skin
 Muscle Antibodies  >333 publications with VR1 and Muscle
 Vascular Antibodies  >276 publications with VR1 and Vascular
 Intestine Antibodies  >165 publications with VR1 and Intestine
 Lung Antibodies  >162 publications with VR1 and Lung
 Kidney Antibodies  >140 publications with VR1 and Kidney
 Mouth Antibodies  >116 publications with VR1 and Mouth
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