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ALDH1L1 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS555411

ALDH1L1 catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. ALDH1L1 expression is tissue-specific and is highly expressed in the liver. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
ALDH1L1, Antibody
Full Product Name
ALDH1L1, Antiserum, Rabbit
Product Gene Name
Species Reactivity
Human, Mouse, Primate, Rat
Form/Format
Whole serum - Liquid
Molecular Weight
55,394 Da
OMIM
600249
Type Info
Rabbit IgG
Immunogen
Full length recombinant human ALDH1L1 expressed and purified from E Coli.
Applications Tested/Suitable for anti-ALDH1L1 antibody
Immunofluorescence (IF), Western Blot (WB)

Testing Data of anti-ALDH1L1 antibody

Image: Neuron-glial cell mixture cultures stained with ALDH1L1 (red) and our monoclonal antibody against GFAP (green). Blue is a DNA stain. ALDH1L1 stains astrocytes and excludes from neuron cells. ALDH1L1 stains the astrocytes cell body and processes, whereas GFAP labels the intermediate filament of the cytoskeleton in subset of astrocytes. Astrocytes are positive for both ALDH1L1 and GFAP appear yellow. ALDH1L1 also labels many astrocytes not labeled by GFAP, which appear as red.
Anti-ALDH1L1 Antibody – Cat# MBS555411

Testing Data of anti-ALDH1L1 antibody

Image: Image: Blot of rat liver tissure homogenates blotted with ALDH1L1. The antibody binds strongly a band at ~100 kDa.
Anti-ALDH1L1 Antibody, Testing Data – Cat# MBS555411

Other Notes

Small volumes of anti-ALDH1L1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ALDH1L1 purchase

MBS555411 is an antibody targeting ALDH1L1. Also known as ALDH1L1, Antiserum, Rabbit. Reactive in Human, Mouse, Primate, Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for ALDH1L1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
ALDH1L1 protein
NCBI Official Synonym Full Names
aldehyde dehydrogenase 1 family member L1
NCBI Official Symbol
ALDH1L1
NCBI Official Synonym Symbols
FDH; FTHFD; 10-fTHF; 10-FTHFDH
UniProt Protein Name
Cytosolic 10-formyltetrahydrofolate dehydrogenase
UniProt Synonym Protein Names
Aldehyde dehydrogenase family 1 member L1
UniProt Gene Name
ALDH1L1
UniProt Synonym Gene Names
FTHFD; 10-FTHFDH; FDH
UniProt Entry Name
AL1L1_HUMAN
NCBI Protein Information
cytosolic 10-formyltetrahydrofolate dehydrogenase

NCBI Summary for ALDH1L1

The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
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UniProt Comments for ALDH1L1

ALDH1L1: 2 isoforms of the human protein are produced by alternative splicing

Protein type: Oxidoreductase; Cofactor and Vitamin Metabolism - one carbon pool by folate; EC 1.5.1.6

Chromosomal Location of Human Ortholog: 3q21.3

Cellular Component: mitochondrion

Molecular Function: methyltransferase activity; aldehyde dehydrogenase (NAD) activity; hydroxymethyl-, formyl- and related transferase activity; formyltetrahydrofolate dehydrogenase activity; catalytic activity

Biological Process: methylation; biosynthetic process; one-carbon compound metabolic process; 10-formyltetrahydrofolate catabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ALDH1L1 antibody

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