Mouse GM-CSF Recombinant Protein – Cat# MBS555489

Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) Mouse Recombinant Protein

Name: GM-CSF Recombinant Protein; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS555489
Price: 240 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS555489

MBS555489 is a recombinant protein targeting GM-CSF. Also known as Recombinant Human Granulocyte Macrophage-Colony Stimulating Factor Pichia Derived. Reactive in Mouse. More details

$240 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF), Recombinant Protein

Full Product Name

Recombinant Human Granulocyte Macrophage-Colony Stimulating Factor Pichia Derived

Product Gene Name

GM-CSF recombinant protein

Species Reactivity

Mouse

Preparation and Storage

Store at 4-8 degrees

Molecular Weight

16,295 Da

OMIM

138960

Product Categories/Family for GM-CSF recombinant protein

Proteins; Growth/Differentiation Factors and Small Molecules; Stem Cell Research Proteins; GM - CSF Mouse

Product References and Citations for GM-CSF recombinant protein

1. Granulocyte-macrophage colony stimulating factor and interleukin-8 in the reproductive tract of ewes following oestrus and mating Reprod Fertil Dev 2007;19(4):585-93.2. Use of granulocyte-macrophage colony-stimulating factor to reverse anergy in otherwise immunologically healthy children. Ann Allergy Asthma Immunol 2007 Apr;98(4):373-82.3. [Plasma granulocyte-macrophage colony stimulating factor (GM-CSF) and activity of enzymes in granulocytes of breast cancer patients] Przegl Lek 2006;63(8):654-7.4. Granulocyte-macrophage colony-stimulating factor (CSF) and macrophage CSF-dependent macrophage phenotypes display differences in cytokine profiles and transcription factor activities: implications for CSF blockade in inflammation. J Immunol 2007 Apr 1 5;178(8):5245-52.5. Granulocyte colony-stimulating factor and granulocyte macrophage colony-stimulating factor exacerbate atherosclerosis in apolipoprotein E-deficient mice. Circulation 2007 Apr 17;115(15):2049-54.6. Re: Clinical and immunological characteristics of patients with serologic progression of prostate cancer achieving long-term disease control with granulocyte-macrophage colony-stimulating factor: B. I. Rini, L. Fong, v. Weinberg, B. Kavanaugh and E. J. Small. J Urol 2006; 175: 2087-2091. J Urol 2007 Apr;177(4):1585; author reply 1585-6.

Other Notes

Small volumes of GM-CSF recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GM-CSF. It may not necessarily be applicable to this product.

NCBI GI #

183364

NCBI GeneID

1437

NCBI Accession #

AAA52578.1

UniProt Secondary Accession #

Q14CE8; Q2VPI8; Q8NFI6

UniProt Related Accession #

P04141

NCBI Official Full Name

GM-CSF

NCBI Official Synonym Full Names

colony stimulating factor 2

NCBI Official Symbol

CSF2

NCBI Official Synonym Symbols

GMCSF

UniProt Protein Name

Granulocyte-macrophage colony-stimulating factor

UniProt Synonym Protein Names

Colony-stimulating factor; CSF; Molgramostin; Sargramostim

Protein Family

Granulocyte-macrophage colony-stimulating factor

UniProt Gene Name

CSF2

UniProt Synonym Gene Names

GMCSF; GM-CSF; CSF

UniProt Entry Name

CSF2_HUMAN

NCBI Protein Information

granulocyte-macrophage colony-stimulating factor

NCBI Summary for GM-CSF

The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq, Jul 2008]

UniProt Comments for GM-CSF

GMCSF: Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. Belongs to the GM-CSF family.

Protein type: Secreted; Cytokine; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 5q31.1

Cellular Component: extracellular space; extracellular region

Molecular Function: protein binding; growth factor activity; granulocyte macrophage colony-stimulating factor receptor binding; cytokine activity

Biological Process: negative regulation of cytolysis; epithelial fluid transport; embryonic placenta development; macrophage activation; positive regulation of tyrosine phosphorylation of Stat5 protein; positive regulation of interleukin-23 production; positive regulation of cell proliferation; immune response; myeloid dendritic cell differentiation; positive regulation of DNA replication

Research Articles on GM-CSF

1. The association of GM-CSF expression with systemic inflammation highlights the potential role of Th17-related cytokines in the pathology of juvenile idiopathic arthritis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with GM-CSF recombinant protein

Products by Pathway	Pathway Diagram
ARMS-mediated Activation Pathway antibodies	ARMS-mediated Activation Pathway Diagram
Amoebiasis Pathway antibodies	Amoebiasis Pathway Diagram
Amoebiasis Pathway antibodies	Amoebiasis Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway antibodies	Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway Diagram
Calcium Signaling In The CD4+ TCR Pathway antibodies	Calcium Signaling In The CD4+ TCR Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokines And Inflammatory Response Pathway antibodies	Cytokines And Inflammatory Response Pathway Diagram

Diseases associated with GM-CSF recombinant protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>54 publications with GM-CSF and Inflammation
Necrosis Antibodies	>31 publications with GM-CSF and Necrosis
Lung Diseases Antibodies	>15 publications with GM-CSF and Lung Diseases
Carcinoma Antibodies	>9 publications with GM-CSF and Carcinoma
Breast Neoplasms Antibodies	>7 publications with GM-CSF and Breast Neoplasms
Neoplasms, Experimental Antibodies	>4 publications with GM-CSF and Neoplasms, Experimental
Lung Neoplasms Antibodies	>4 publications with GM-CSF and Lung Neoplasms
Leukemia, Myeloid, Acute Antibodies	>3 publications with GM-CSF and Leukemia, Myeloid, Acute
Arthritis, Rheumatoid Antibodies	>3 publications with GM-CSF and Arthritis, Rheumatoid
Anemia Antibodies	>3 publications with GM-CSF and Anemia

Organs/Tissues associated with GM-CSF recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>63 publications with GM-CSF and Blood
Bone Antibodies	>21 publications with GM-CSF and Bone
Lung Antibodies	>19 publications with GM-CSF and Lung
Intestine Antibodies	>3 publications with GM-CSF and Intestine