Microtubular-Assoicated Protein (MAP2) Antibody

MAP2 belongs to the microtubule-associated protein (MAP) family that also includes MAP1A, MAP1B, MAP1C, MAP4 and tau. These proteins of this family stabilize and promote the assembly of microtubules; which is an essential step in neurogenesis. MAP2 is made up of two ~280kDa apparent molecular weight bands referred to as MAP2a and MAP2b. A third lower molecular weight form, usually called MAP2c, corresponds to a pair of protein bands running at ~70kDa on SDS-PAGE gels. All these MAP2 forms are derived from a single gene by alternate transcription, and all share a C-terminal sequence which includes either three or four microtubule binding peptide sequences, which are very similar to those found in the related microtubule binding protein tau. MAP2 isoforms are expressed only in neuronal cells and specifically in the perikarya and dendrites of these cells. Antibodies to MAP2 are therefore excellent markers on neuronal cells, their perikarya and neuronal dendrites. In contrast tau is found predominantly in neuronal axons.

Small volumes of anti-MAP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS555588 is an antibody targeting MAP2. Also known as Microtubular-Assoicated Protein (MAP2), Affinity Purified Antibody. Reactive in Human, Mouse.