Laminin 111 Antibody – Rabbit Polyclonal

Laminins are high-molecular weight (~400kDa) proteins of the extracellular matrix. They are an important and biologically active part of the basal lamina, which is one of the layers of the basement membrane, a protein network foundation for most cells and organs, influencing cell differentiation, migration, and adhesion. Laminins are heterotrimeric proteins that contain an alpha-chain, a beta-chain, and a gamma-chain. The distribution of the different laminin isoforms is tissue-specific. The laminin molecules are named according to their chain composition.
Laminin-111 is one of the first laminin isoforms to be discovered. The "111" identifies the isoform's chain composition of alpha1beta1gamma1. Laminin-111 is predominantly expressed in the embryonic epithelium, but can also be found in some adult epithelium such as the kidney,liver, testis, ovaries, and brain blood vessels. Laminin-111 has been identified as a crucial molecule for development of the embryo, genetic ablation of laminin-111 results in embryonic death.

Small volumes of anti-Laminin 111 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS555738 is an antibody targeting Laminin 111. Also known as Laminin 111, Affinity Purified, Rabbit. Reactive in Mouse. Host: Rabbit.