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TNFRH2; TNFRSF 22 Antibody – Rat Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS565034

MBS565034 is an antibody targeting TNFRH2; TNFRSF 22. Also known as DcTRAIL-R2 (mouse) monoclonal antibody (Lucy-1). Reactive in MouseDoes not cross-react with mouse DcTRAIL-R1.. Host: Rat: Purified from concentrated hybridoma tissue culture supernatant. More details

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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
DcTRAIL-R2 (TNFRH2; TNFRSF 22), Monoclonal Antibody
Full Product Name
DcTRAIL-R2 (mouse) monoclonal antibody (Lucy-1)
Product Synonym Names
DcTRAIL-R2
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
Lucy-1
Host
Rat: Purified from concentrated hybridoma tissue culture supernatant.
Species Reactivity
Mouse
Does not cross-react with mouse DcTRAIL-R1.
Form/Format
Liquid. In PBS containing 0.02% sodium azide.
Specificity
Recognizes mouse DcTRAIL-R2. Does not cross-react with mouse DcTRAIL-R1.
Preparation and Storage
Long term: -20 degree C
Short term: 4 degree C
Stable for at least one year after receipt if stored at -20 degree C.
Avoid freeze/thaw cycles.
Molecular Weight
20,227 Da
3D Structure
ModBase 3D Structure for Q9ER62
Immunogen
Recombinant mouse DcTRAIL-R2 extracelluar domain (aa 1-170).

Product Categories/Family for anti-TNFRH2; TNFRSF 22 antibody

Applications Tested/Suitable for anti-TNFRH2; TNFRSF 22 antibody
Flow Cytometry (FC/FACS)
Application Notes for anti-TNFRH2; TNFRSF 22 antibody
Flow Cytometry (1:1,000)
Suggested dilutions/conditions may not be available for all applications.
Not suitable for immunoprecipitation.

Flow Cytometry (FC/FACS) of anti-TNFRH2; TNFRSF 22 antibody

Figure: FACS analysis of cells with MAb to DcTRAIL-R2 (Lucy-1) .Method: HEK 293T cells were mock transfected (thin line) or transfected with an expression plasmid enabling surface expression of the extracellular domain of mouse DcTRAIL-R2 (thick line). Cells (5x105) were incubated on ice for 30 min. in 50ul FACS buffer (PBS, 5% fetal calf serum, 0.02% azide) containing 1ug/ml of monoclonal antibody to DcTRAIL-R2 (Lucy-1) . After washing in FACS buffer, PE-conjugated antibody to rat IgG was added. Cells were incubated on ice for 30 min., washed and then analyzed by flow cytometry.
Rat Anti-TNFRH2; TNFRSF 22 Monoclonal Antibody – Cat# MBS565034

Other Notes

Small volumes of anti-TNFRH2; TNFRSF 22 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TNFRH2; TNFRSF 22. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Tumor necrosis factor receptor superfamily member 22
NCBI Official Synonym Full Names
tumor necrosis factor receptor superfamily, member 22
NCBI Official Symbol
Tnfrsf22
NCBI Official Synonym Symbols
SOBa; Tnfrh2; Tnfrsf1al2; mDcTrailr2; 2810028K06Rik; C130035G06Rik
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 22
UniProt Synonym Protein Names
Decoy TRAIL receptor 2; TNF receptor family member SOBa; TNF receptor homolog 2; Tumor necrosis factor receptor p60 homolog 2
UniProt Gene Name
Tnfrsf22
UniProt Synonym Gene Names
Dctrailr2; Tnfrh2; Tnfrsf1al2
UniProt Entry Name
TNR22_MOUSE
NCBI Protein Information
tumor necrosis factor receptor superfamily member 22

UniProt Comments for TNFRH2; TNFRSF 22

TNFRSF22: Receptor for the cytotoxic ligand TNFSF10/TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. Protects cells against TRAIL mediated apoptosis possibly through ligand competition. Cannot induce the NF-kappa-B pathway.

Cellular Component: external side of plasma membrane; extracellular region; integral to membrane; membrane; plasma membrane

Molecular Function: protein binding; receptor activity; TRAIL binding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-TNFRH2; TNFRSF 22 antibody

Organs/Tissues associated with anti-TNFRH2; TNFRSF 22 antibody

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