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BAFF Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS565046

MBS565046 is an antibody targeting BAFF. Also known as BAFF (human) monoclonal antibody (Buffy-XI). Reactive in HumanDoes not cross-react with mouse BAFF.. Host: Mouse: Purified from concentrated hybridoma tissue culture supernatant. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
BAFF, Monoclonal Antibody
Full Product Name
BAFF (human) monoclonal antibody (Buffy-XI)
Product Gene Name
Product Synonym Names
B cell-activating factor; BLyS; TALL-1; THANK; zTNF4; TNFSF 13B/20; CD257
Clonality
Monoclonal
Isotype
IgG1
Clone Number
Buffy-XI
Host
Mouse: Purified from concentrated hybridoma tissue culture supernatant.
Species Reactivity
Human
Does not cross-react with mouse BAFF.
Form/Format
Liquid. Antibody in PBS containing 0.02% sodium azide.
Specificity
Recognizes the C-terminus but not the stalk of human BAFF.
Preparation and Storage
Long term: -20 degree C
Short term: 4 degree C
Avoid freeze/thaw cycles. Stable for at least 1 year after receipt when stored as recommended.
Molecular Weight
17,578 Da
OMIM
603969
3D Structure
ModBase 3D Structure for Q9Y275
Immunogen
Extracellular domain of human BAFF (aa 137-285).
Applications Tested/Suitable for anti-BAFF antibody
Western Blot (WB)
Application Notes for anti-BAFF antibody
Western Blot (1ug/ml)
Suggested dilutions/conditions may not be available for all applications.

Western Blot (WB) of anti-BAFF antibody

Figure: Western blot of total cell extracts from HEK 293 cells transfected with the indicated expression vector.Method: 10ug of total protein lysate was applied to the gel. MAb to BAFF (Buffy-XI) was used at 1ug/ml and revealed with HRP-coupled anti-mouse secondary antibody (1:4'000).
Mouse Anti-BAFF Monoclonal Antibody – Cat# MBS565046

Other Notes

Small volumes of anti-BAFF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for BAFF. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Tumor necrosis factor ligand superfamily member 13B
NCBI Official Synonym Full Names
tumor necrosis factor superfamily member 13b
NCBI Official Symbol
TNFSF13B
NCBI Official Synonym Symbols
DTL; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNLG7A; TNFSF20
UniProt Protein Name
Tumor necrosis factor ligand superfamily member 13B
UniProt Synonym Protein Names
B lymphocyte stimulator; BLyS
UniProt Gene Name
TNFSF13B
UniProt Synonym Gene Names
BAFF; BLYS; TALL1; TNFSF20; ZTNF4; BLyS; TALL-1
UniProt Entry Name
TN13B_HUMAN
NCBI Protein Information
tumor necrosis factor ligand superfamily member 13B

NCBI Summary for BAFF

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]
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UniProt Comments for BAFF

Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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