Rat Anti-LT beta R Monoclonal Antibody – Cat# MBS565068

Flow cytometry analysis of C57BL/6 bone marrow cells stained with purified LT beta R (mouse), mAb (5G11) conjugated to PE (Upper panel) or rat IgG2a isotype control PE (Lower panel) and Ly-6G/Ly-6C FITC.

LT beta R Antibody – Rat Monoclonal

Name: LT beta R Antibody; Monoclonal; Rat; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS565068
Price: 520 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS565068

LT beta R is involved in peripheral lymphoid tissue organogenesis and function. The LT alpha /LT beta R receptor system may also have some function in early embryogenesis. LT beta R is a type I transmembrane glycoprotein and member of the TNF receptor… More details

$520 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

LT beta R, Monoclonal Antibody

Full Product Name

LT beta R (mouse) monoclonal antibody (5G11)

Product Gene Name

anti-LT beta R antibody

Product Synonym Names

Lymphotoxin- beta receptor; TNFRSF 3; Tumor necrosis factor receptor 2 related protein; Tumor necrosis factor C receptor; Tumor necrosis factor receptor superfamily member 3 [precursor]

Clonality

Monoclonal

Isotype

IgG2a

Clone Number

5G11

Host

Rat

Species Reactivity

Mouse

Form/Format

Liquid. In PBS, pH 7.2, containing 0.09% sodium azide.

Purity/Purification

Affinity Purified

Specificity

Recognizes mouse LTbetaR.

Preparation and Storage

Long term storage: 4 degree C

Molecular Weight

44,956 Da

3D Structure

ModBase 3D Structure for P50284

Immunogen

Extracellular domain of mouse LT beta R (lymphotoxin beta receptor) expressed in E Coli.

Product Categories/Family for anti-LT beta R antibody

Cell Signaling

Applications Tested/Suitable for anti-LT beta R antibody

Flow Cytometry (FC/FACS)

Other Notes

Small volumes of anti-LT beta R antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LT beta R purchase

MBS565068 is an antibody targeting LT beta R. Also known as LT beta R (mouse) monoclonal antibody (5G11). Reactive in Mouse. Host: Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for LT beta R. It may not necessarily be applicable to this product.

NCBI GI #

1729988

NCBI GeneID

17000

NCBI Accession #

P50284.1

UniProt Primary Accession #

P50284

UniProt Related Accession #

P50284

NCBI Official Full Name

Tumor necrosis factor receptor superfamily member 3

NCBI Official Synonym Full Names

lymphotoxin B receptor

NCBI Official Symbol

Ltbr

NCBI Official Synonym Symbols

CD18; Ltar; TNFCR; Tnfbr; TNFRrp; LTbetaR; TNFR-RP; Tnfrsf3; AI256028; TNFR2-RP; TNF-R-III

UniProt Protein Name

Tumor necrosis factor receptor superfamily member 3

UniProt Synonym Protein Names

Lymphotoxin-beta receptor

Protein Family

Lactoyl-CoA dehydratase

UniProt Gene Name

Ltbr

UniProt Synonym Gene Names

Tnfcr; Tnfrsf3

UniProt Entry Name

TNR3_MOUSE

NCBI Protein Information

tumor necrosis factor receptor superfamily member 3

UniProt Comments for LT beta R

LTBR: Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs.

Protein type: Membrane protein, integral

Cellular Component: integral to membrane; integral to plasma membrane; membrane

Molecular Function: identical protein binding; protein binding; tumor necrosis factor receptor activity; ubiquitin protein ligase binding

Biological Process: apoptosis; immune response; inflammatory response; lymph node development; myeloid dendritic cell differentiation; positive regulation of JNK cascade; positive regulation of MAPKKK cascade; regulation of apoptosis; regulation of cell proliferation; response to lipopolysaccharide

Research Articles on LT beta R

1. our results reveal a novel role for LTbetaR signaling in epithelial cells in the regulation of intestinal epithelial cell homeostasis to limit mucosal damage.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-LT beta R antibody

Reference Product	PubMed Publications
Tnfsf14 antibody	>40 publications with LT beta R and Tnfsf14
Ltb antibody	>40 publications with LT beta R and Ltb
Traf3 antibody	>15 publications with LT beta R and Traf3
Traf2 antibody	>12 publications with LT beta R and Traf2
Traf5 antibody	>8 publications with LT beta R and Traf5
Lta antibody	>7 publications with LT beta R and Lta
Madcam1 antibody	>4 publications with LT beta R and Madcam1
Adipor1 antibody	>1 publications with LT beta R and Adipor1
Map3k14 antibody	>1 publications with LT beta R and Map3k14

Pathways associated with anti-LT beta R antibody

Products by Pathway	Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
HIF-1 Signaling Pathway antibodies	HIF-1 Signaling Pathway Diagram
HTLV-I Infection Pathway antibodies	HTLV-I Infection Pathway Diagram
HTLV-I Infection Pathway antibodies	HTLV-I Infection Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Intestinal Immune Network For IgA Production Pathway antibodies	Intestinal Immune Network For IgA Production Pathway Diagram
Intestinal Immune Network For IgA Production Pathway antibodies	Intestinal Immune Network For IgA Production Pathway Diagram
NF-kappa B Signaling Pathway antibodies	NF-kappa B Signaling Pathway Diagram

Diseases associated with anti-LT beta R antibody

Disease Name	Pubmed Publications
Necrosis Antibodies	>182 publications with LT beta R and Necrosis
Inflammation Antibodies	>40 publications with LT beta R and Inflammation
Disease Models, Animal Antibodies	>14 publications with LT beta R and Disease Models, Animal
Nervous System Diseases Antibodies	>13 publications with LT beta R and Nervous System Diseases
Carcinoma, Squamous Cell Antibodies	>9 publications with LT beta R and Carcinoma, Squamous Cell
Liver Diseases Antibodies	>6 publications with LT beta R and Liver Diseases
Breast Neoplasms Antibodies	>5 publications with LT beta R and Breast Neoplasms
Weight Loss Antibodies	>4 publications with LT beta R and Weight Loss
Neoplasms, Experimental Antibodies	>4 publications with LT beta R and Neoplasms, Experimental
Cardiovascular Diseases Antibodies	>4 publications with LT beta R and Cardiovascular Diseases

Organs/Tissues associated with anti-LT beta R antibody

Organ/Tissue Name	Pubmed Publications
Spleen Antibodies	>49 publications with LT beta R and Spleen
Bone Antibodies	>43 publications with LT beta R and Bone
Bone Marrow Antibodies	>27 publications with LT beta R and Bone Marrow
Thymus Antibodies	>21 publications with LT beta R and Thymus
Intestine Antibodies	>21 publications with LT beta R and Intestine
Embryonic Tissue Antibodies	>20 publications with LT beta R and Embryonic Tissue
Liver Antibodies	>14 publications with LT beta R and Liver
Skin Antibodies	>11 publications with LT beta R and Skin
Lung Antibodies	>7 publications with LT beta R and Lung
Eye Antibodies	>6 publications with LT beta R and Eye