Mouse Anti-MKK1; MAP kinase kinase 1 Monoclonal Antibody – Cat# MBS565093

Western blot analysis of MEK1: Lane 1: MW marker, Lane 2: GST-tagged recombinant MEK1

MKK1; MAP kinase kinase 1 Antibody – Mouse Monoclonal

Name: MKK1; MAP kinase kinase 1 Antibody; Monoclonal; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS565093
Price: 435 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS565093

MEK is a dual specificity kinase capable of phosphorylating both tyrosine and threonine residues. The MEK family, which is also known as MAP kinase kinase, phosphorylates MAP kinases on the conserved T-X-Y motif; phosphorylation of MAPK by MEK results in an… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

MEK1 (MKK1; MAP kinase kinase 1), Monoclonal Antibody

Full Product Name

MEK1 monoclonal antibody (3D9)

Product Gene Name

anti-MKK1; MAP kinase kinase 1 antibody

Product Synonym Names

MEK1

Clonality

Monoclonal

Isotype

IgG1

Clone Number

3D9

Host

Mouse

Species Reactivity

Human

Form/Format

Liquid. In PBS containing 0.1% sodium azide. Concentration 1mg/ml.

Purity/Purification

Protein G affinity purified.

Specificity

Recognizes human MEK1. Detects a band of ~45kDa (or ~71kDa with GST tag) by Western blot.

Preparation and Storage

Long term storage: -20 degree C
Avoid freeze/thaw cycles.

Molecular Weight

34,087 Da

Immunogen

Native MEK and recombinant MEK1.

Product Categories/Family for anti-MKK1; MAP kinase kinase 1 antibody

Posttranslational Modifications; Cell Signaling

Applications Tested/Suitable for anti-MKK1; MAP kinase kinase 1 antibody

ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)

Application Notes for anti-MKK1; MAP kinase kinase 1 antibody

Immunohistochemistry (1ug/ml)
Suggested dilutions/conditions may not be available for all applications.
Detects a band of ~45kDa (or ~71kDa with GST tag) by Western blot.

Other Notes

Small volumes of anti-MKK1; MAP kinase kinase 1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MKK1; MAP kinase kinase 1 purchase

MBS565093 is an antibody targeting MKK1; MAP kinase kinase 1. Also known as MEK1 monoclonal antibody (3D9). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for MKK1; MAP kinase kinase 1. It may not necessarily be applicable to this product.

NCBI GI #

2196704

NCBI Accession #

AAB97145.1

UniProt Secondary Accession #

O04440; O04661

NCBI Official Full Name

MEK1

UniProt Protein Name

Mitogen-activated protein kinase kinase 1

UniProt Synonym Protein Names

AtMEK1; NMAPKK

Protein Family

Meiosis-specific serine/threonine-protein kinase

UniProt Gene Name

MKK1

UniProt Synonym Gene Names

MEK1; AtMKK1; MAP kinase kinase 1

UniProt Entry Name

M2K1_ARATH

UniProt Comments for MKK1; MAP kinase kinase 1

MEKK1, MKK1/MKK2 and MPK4/MPK6 function in a signaling pathway that modulates the expression of genes responding to biotic and abiotic stresses and also plays an important role in pathogen defense by negatively regulating innate immunity. Activates by phosphorylation the downstream MPK4. Acts redundantly with MKK2. MKK1-MPK6 module mediates abscisic acid (ABA)-dependent CAT1 expression with H2O2 production and response to drought and salt stress. MKK1-MPK6 module is also involved in sugar signaling during the process of seed germination.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.