Mouse Anti-IDO1 Monoclonal Antibody – Cat# MBS565098

Figure 1. Total cell lysate from 293E cells untransfected (lane 1) and 293E transfected with IDO1 (lane 2) were resolved by electrophoresis, transferred to nitrocellulose, and probed with IDO1 (mouse), mAb (2E2). Proteins were visualized using a goat anti-mouse-IgG secondary conjugated to HRP and chemiluminescence detection.

IDO1 Antibody – Mouse Monoclonal

Name: IDO1 Antibody; Monoclonal; Mouse; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS565098
Price: 545 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS565098

Indoleamine 2,3-dioxygenase (IDO) is an IFN-gamma inducible gene. It catalyzes the degradation of the essential amino acid L-tryptophan to N-formylkynurenine. IDO has been implicated to protect against intracellular and extracellular pathogens.. IDO1 is also… More details

$545 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

IDO1, Monoclonal Antibody

Full Product Name

IDO1 (mouse) monoclonal antibody (2E2)

Product Gene Name

anti-IDO1 antibody

Product Synonym Names

INDO; Indoleamine 2,3-dioxygenase; Indole 2,3-dioxygenase; Indoleamine-pyrrole 2,3-dioxygenase

Clonality

Monoclonal

Isotype

IgG1

Clone Number

2E2

Host

Mouse

Species Reactivity

Mouse

Form/Format

Liquid. In PBS, pH 7.2, containing 0.09% sodium azide.

Purity/Purification

Protein G-affinity purified.

Specificity

Recognizes mouse IDO1.

Preparation and Storage

Long term storage: 4 degree C

Molecular Weight

45,641 Da

3D Structure

ModBase 3D Structure for P28776

Immunogen

Recombinant mouse IDO1.

Product Categories/Family for anti-IDO1 antibody

Cell Signaling

Applications Tested/Suitable for anti-IDO1 antibody

Western Blot (WB)

Other Notes

Small volumes of anti-IDO1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IDO1 purchase

MBS565098 is an antibody targeting IDO1. Also known as IDO1 (mouse) monoclonal antibody (2E2). Reactive in Mouse. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for IDO1. It may not necessarily be applicable to this product.

NCBI GI #

123949

NCBI GeneID

15930

NCBI Accession #

P28776.1

UniProt Primary Accession #

P28776

UniProt Related Accession #

P28776

NCBI Official Full Name

Indoleamine 2,3-dioxygenase 1

NCBI Official Synonym Full Names

indoleamine 2,3-dioxygenase 1

NCBI Official Symbol

Ido1

NCBI Official Synonym Symbols

Ido; Indo

UniProt Protein Name

Indoleamine 2,3-dioxygenase 1

UniProt Synonym Protein Names

Indoleamine-pyrrole 2,3-dioxygenase

Protein Family

Indoleamine 2,3-dioxygenase

UniProt Gene Name

Ido1

UniProt Synonym Gene Names

Ido; Indo; IDO-1

UniProt Entry Name

I23O1_MOUSE

NCBI Protein Information

indoleamine 2,3-dioxygenase 1

UniProt Comments for IDO1

INDO: Catalyzes the cleavage of the pyrrol ring of tryptophan and incorporates both atoms of a molecule of oxygen. Belongs to the indoleamine 2,3-dioxygenase family.

Protein type: EC 1.13.11.52; Cell cycle regulation; Amino Acid Metabolism - tryptophan; Oxidoreductase

Cellular Component: cytoplasm; cytosol; smooth muscle contractile fiber; stereocilium bundle

Molecular Function: amino acid binding; dioxygenase activity; heme binding; indoleamine 2,3-dioxygenase activity; metal ion binding; oxidoreductase activity; oxygen binding; protein binding; tryptophan 2,3-dioxygenase activity

Biological Process: cytokine production during acute inflammatory response; defense response; immune system process; inflammatory response; multicellular organismal response to stress; negative regulation of activated T cell proliferation; negative regulation of interleukin-10 production; negative regulation of T cell proliferation; positive regulation of apoptosis; positive regulation of chronic inflammatory response; positive regulation of interleukin-12 production; positive regulation of T cell tolerance induction; positive regulation of T-helper 2 type immune response; response to lipopolysaccharide; tryptophan catabolic process; tryptophan catabolic process to kynurenine

Research Articles on IDO1

1. TNF-alpha mediates stress-induced depression by upregulating indoleamine 2,3-dioxygenase in a mouse model of unpredictable chronic mild stress.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IDO1 antibody

Reference Product	PubMed Publications
Kynu antibody	>3 publications with IDO1 and Kynu
Cyp1a1 antibody	>1 publications with IDO1 and Cyp1a1
Tph1 antibody	>1 publications with IDO1 and Tph1

Pathways associated with anti-IDO1 antibody

Products by Pathway	Pathway Diagram
African Trypanosomiasis Pathway antibodies	African Trypanosomiasis Pathway Diagram
African Trypanosomiasis Pathway antibodies	African Trypanosomiasis Pathway Diagram
Histidine, Lysine, Phenylalanine, Tyrosine, Proline And Tryptophan Catabolism Pathway antibodies	Histidine, Lysine, Phenylalanine, Tyrosine, Proline And Tryptophan Catabolism Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Amino Acids And Derivatives Pathway antibodies	Metabolism Of Amino Acids And Derivatives Pathway Diagram
NAD Biosynthesis II (from Tryptophan) Pathway antibodies	NAD Biosynthesis II (from Tryptophan) Pathway Diagram
Tryptophan Catabolism Pathway antibodies	Tryptophan Catabolism Pathway Diagram
Tryptophan Metabolism Pathway antibodies	Tryptophan Metabolism Pathway Diagram
Tryptophan Metabolism Pathway antibodies	Tryptophan Metabolism Pathway Diagram

Diseases associated with anti-IDO1 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>66 publications with IDO1 and Inflammation
Colitis Antibodies	>11 publications with IDO1 and Colitis
Neoplasms, Experimental Antibodies	>11 publications with IDO1 and Neoplasms, Experimental
Neurodegenerative Diseases Antibodies	>8 publications with IDO1 and Neurodegenerative Diseases
Lung Diseases Antibodies	>8 publications with IDO1 and Lung Diseases
Necrosis Antibodies	>7 publications with IDO1 and Necrosis
Liver Diseases Antibodies	>6 publications with IDO1 and Liver Diseases
Breast Neoplasms Antibodies	>6 publications with IDO1 and Breast Neoplasms
Cognition Disorders Antibodies	>4 publications with IDO1 and Cognition Disorders
Endometriosis Antibodies	>4 publications with IDO1 and Endometriosis

Organs/Tissues associated with anti-IDO1 antibody

Organ/Tissue Name	Pubmed Publications
Intestine Antibodies	>8 publications with IDO1 and Intestine
Epididymis Antibodies	>3 publications with IDO1 and Epididymis