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USE1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS565204

UBA6 (ubiquitin-like modifier activating enzyme-6, also known as UbE1L2) is a novel ubiquitin activating enzyme that is also capable of activating the ubiquitin-like protein FAT10 (human leukocyte antigen F-associated transcript 10), which, similarly to… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Use1, Polyclonal Antibody
Full Product Name
Use1 (human) polyclonal antibody
Product Gene Name
Product Synonym Names
E2Z; Uba6-specific E2 conjugating enzyme 1; Ubiquitin-protein ligase Z; Ubiquitin carrier protein Z
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. In PBS containing 0.01% sodium azide.
Purity/Purification
Crude serum.
Specificity
Recognizes human use1 protein.
Preparation and Storage
Long term: -20 degree C
Short term: 4 degree C
Stable for at least 1 year after receipt when stored at -20 degree C. Store diluted antibody at 2-4 degree C and use within 1 month. Dilute with PBS pH 7.2-7.4 and 1% normal goat serum (if a goat-anti-rabbit IgG linker antibody is to be used).
Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20 degree C.
Molecular Weight
28,075 Da
OMIM
611362
3D Structure
ModBase 3D Structure for Q9H832
Immunogen
Synthetic peptide corresponding to residues 231-242 of human use1 protein.
Applications Tested/Suitable for anti-Use1 antibody
Western Blot (WB)
Application Notes for anti-Use1 antibody
Western Blot (1:1,000)
Suggested dilutions/conditions may not be available for all applications.

Other Notes

Small volumes of anti-Use1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Use1 purchase

MBS565204 is an antibody targeting Use1. Also known as Use1 (human) polyclonal antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Use1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Ubiquitin-conjugating enzyme E2 Z
NCBI Official Synonym Full Names
ubiquitin conjugating enzyme E2 Z
NCBI Official Symbol
UBE2Z
NCBI Official Synonym Symbols
USE1; HOYS7
UniProt Protein Name
Ubiquitin-conjugating enzyme E2 Z
UniProt Synonym Protein Names
E2 ubiquitin-conjugating enzyme Z; Uba6-specific E2 conjugating enzyme 1; Use1; Ubiquitin carrier protein Z; Ubiquitin-protein ligase Z
UniProt Gene Name
UBE2Z
UniProt Synonym Gene Names
Use1
UniProt Entry Name
UBE2Z_HUMAN
NCBI Protein Information
ubiquitin-conjugating enzyme E2 Z

NCBI Summary for Use1

This gene encodes an enzyme which ubiquitinates proteins which participate in signaling pathways and apoptosis. [provided by RefSeq, Feb 2012]

UniProt Comments for Use1

UBE2Z: Catalyzes the covalent attachment of ubiquitin to other proteins. Specific substrate for UBA6, not charged with ubiquitin by UBE1. May be involved in apoptosis regulation. Belongs to the ubiquitin-conjugating enzyme family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Ligase; Ubiquitin conjugating system; Ubiquitin ligase; EC 6.3.2.19

Chromosomal Location of Human Ortholog: 17q21.32

Cellular Component: cytoplasm; nucleoplasm

Molecular Function: ATP binding; protein binding; ubiquitin protein ligase binding

Biological Process: apoptosis; protein ubiquitination during ubiquitin-dependent protein catabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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