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Synapsin II (SYN2) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS565237

Synapsin I, II and III belong to a family of neuron-specific phosphoproteins which maintain a reserve pool of vesicles in the vicinity of the active zone by tethering synaptic vesicles to each other and to an Actin-based cytoskeleton meshwork. They have been… More details

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Product Overview

Online Datasheet in PDF
Product Name
Synapsin II (SYN2), Polyclonal Antibody
Full Product Name
Synapsin II polyclonal antibody
Product Gene Name
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse, Rat
Form/Format
Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
Purity/Purification
Protein A affinity purified.
Specificity
Recognizes mouse and rat synapsin II. Detects a band of ~74kDa (synapsin Iia) and ~54kDa (synapsin Iib) by Western blot.
Preparation and Storage
Long term storage: -20 degree C
Avoid freeze/thaw cycles.
Molecular Weight
52,455 Da
3D Structure
ModBase 3D Structure for Q63537
Immunogen
Synthetic peptide corresponding to a portion of rat Synapsin II. The sequence is completely conserved in mouse.
Applications Tested/Suitable for anti-SYN2 antibody
Immunoprecipitation (IP), Western Blot (WB)
Application Notes for anti-SYN2 antibody
Immunoprecipitation (1:100)
Western Blot (1ug/ml, colorimetric)
Suggested dilutions/conditions may not be available for all applications.
Detects a band of ~74kDa (synapsin Iia) and ~54kDa (synapsin Iib) by Western blot.

Other Notes

Small volumes of anti-SYN2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SYN2 purchase

MBS565237 is an antibody targeting SYN2. Also known as Synapsin II polyclonal antibody. Reactive in Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SYN2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Synapsin-2
NCBI Official Synonym Full Names
synapsin II
NCBI Official Symbol
Syn2
UniProt Protein Name
Synapsin-2
UniProt Synonym Protein Names
Synapsin II
UniProt Gene Name
Syn2
UniProt Entry Name
SYN2_RAT
NCBI Protein Information
synapsin-2

NCBI Summary for SYN2

neuronal phosphoprotein that coats synaptic vesicles; binds to the cytoskeleton; may be important for vesicle trafficking to synapses and for the regulation of neurotransmitter release [RGD, Feb 2006]

UniProt Comments for SYN2

SYN2: neuronal phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal and to the cytoskeleton. May function in the regulation of neurotransmitter release and synaptogenesis. Mutations in this gene may be associated with abnormal presynaptic function and schizophrenia. Alternative splicing results in two isoforms.

Protein type: Vesicle

Cellular Component: cell junction; myelin sheath; synapse; synaptic vesicle; synaptic vesicle membrane; terminal button

Molecular Function: ATP binding; calcium-dependent protein binding; catalytic activity; cytoskeletal protein binding; protein binding

Biological Process: neurotransmitter secretion; regulation of neurotransmitter secretion
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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