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MEKK3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS565725

MEKKs (Mitogen activated protein kinase kinase kinases) are serine-threonine kinases that act as the first tier of cellular MAP kinase pathways by activation of MAP/ERK kinases, or MEKs. Many enzymes with MEKK activity have been identified, including MEKK1-4,… More details

$510 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MEKK3, Polyclonal Antibody
Full Product Name
MEKK3 polyclonal antibody
Product Gene Name
Product Synonym Names
MAP3K3; MEK kinase 3; MEKK3, pAb
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Sheep, Dog, Pig, Monkey, Drosophila, Guinea pig, Hamster, Rabbit, Xenopus
Form/Format
Liquid. Whole rabbit serum.
Specificity
Recognizes human, mouse, rat, dog, Drosophila, guinea pig, hamster, monkey, pig, rabbit, sheep and Xenopus MEKK3.
Preparation and Storage
Long Term: -20 degree C
Avoid freeze/thaw cycles.
Molecular Weight
70,776 Da
3D Structure
ModBase 3D Structure for Q61084
Immunogen
Synthetic peptide corresponding to the sequence near the N-terminus of mouse MEKK3.
Applications Tested/Suitable for anti-MEKK3 antibody
Immunohistochemistry (IHC), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes for anti-MEKK3 antibody
Western Blot (1:5000).

Immunohistochemistry (IHC) of anti-MEKK3 antibody

IHC Analysis: Human uterus tissue stained with MEKK3, pAb at 1:100.
Rabbit Anti-MEKK3 Polyclonal Antibody – Cat# MBS565725

Other Notes

Small volumes of anti-MEKK3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MEKK3 purchase

MBS565725 is an antibody targeting MEKK3. Also known as MEKK3 polyclonal antibody. Reactive in Human, Mouse, Rat, Sheep, Dog, Pig, Monkey, Drosophila, Guinea pig, Hamster, Rabbit, Xenopus. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MEKK3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
Mitogen-activated protein kinase kinase kinase 3
NCBI Official Synonym Full Names
mitogen-activated protein kinase kinase kinase 3
NCBI Official Symbol
Map3k3
NCBI Official Synonym Symbols
Mekk3; MAPKKK3; AW548911; mKIAA4031
UniProt Protein Name
Mitogen-activated protein kinase kinase kinase 3
UniProt Synonym Protein Names
MAPK/ERK kinase kinase 3; MEK kinase 3; MEKK 3
UniProt Gene Name
Map3k3
UniProt Synonym Gene Names
Mekk3; MEK kinase 3; MEKK 3
NCBI Protein Information
mitogen-activated protein kinase kinase kinase 3

UniProt Comments for MEKK3

MEKK3: a protein kinase of the STE11 family. Phosphorylated and activated by MLK3 and TAK1. Phosphorylates and activates MEK5.

Protein type: EC 2.7.11.25; Kinase, protein; Protein kinase, STE; Protein kinase, Ser/Thr (non-receptor); STE group; STE11 family

Chromosomal Location of Human Ortholog: 11|11 E1

Cellular Component: cytoplasm

Molecular Function: protein binding; protein kinase activity; receptor signaling protein serine/threonine kinase activity

Biological Process: blood vessel development; protein amino acid autophosphorylation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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