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Vasopressin Receptor V1a (AVPR1A) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS565849

Arginine vasopressin (AVP) is a nonapeptide hormone produced in magnocellular neurons of the hypothalamus, which functions as an antidiuretic in the kidney and systemically as a regulator of vasoconstriction, blood volume, and blood pressure. AVP acts by… More details

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Product Overview

Online Datasheet in PDF
Product Name
Vasopressin receptor V1a (Avpr1a), Polyclonal Antibody
Full Product Name
Vasopressin receptor V1a polyclonal antibody
Product Gene Name
anti-Avpr1a antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Predicted species reactivity based on epitope sequence homology: rhesus macaque, dog, bovine
Form/Format
Liquid. In PBS containing 50% glycerol and 0.01% sodium azide
Purity/Purification
Peptide Affinity purified
Preparation and Storage
For long term storage, store at -20 degree C
Shipping: Shipped on Blue Ice
Molecular Weight
47,655 Da
3D Structure
ModBase 3D Structure for P30560
Immunogen
Synthetic peptide corresponding to the sequence near the N-terminus of rat vasopressin receptor V1a

Product Categories/Family for anti-Avpr1a antibody

Cellular Analysis; Cell Signaling
Applications Tested/Suitable for anti-Avpr1a antibody
Western Blot (WB)

Other Notes

Small volumes of anti-Avpr1a antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Avpr1a purchase

MBS565849 is an antibody targeting Avpr1a. Also known as Vasopressin receptor V1a polyclonal antibody. Reactive in Human, Mouse, Rat
Predicted species reactivity based on epitope sequence homology: rhesus macaque, dog, bovine. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Avpr1a. It may not necessarily be applicable to this product.

NCBI GI #
108935913
NCBI GeneID
25107
NCBI Accession #
P30560.4
UniProt Primary Accession #
P30560
UniProt Secondary Accession #
Q5M8D1; Q62874; Q9QW18
UniProt Related Accession #
P30560
NCBI Official Full Name
Vasopressin V1a receptor
NCBI Official Synonym Full Names
arginine vasopressin receptor 1A
NCBI Official Symbol
Avpr1a
NCBI Official Synonym Symbols
V1a; AVPR; V1aR
UniProt Protein Name
Vasopressin V1a receptor
UniProt Synonym Protein Names
AVPR V1a; Antidiuretic hormone receptor 1a; Vascular/hepatic-type arginine vasopressin receptor
Protein Family
Vasopressin V1a receptor
UniProt Gene Name
Avpr1a
UniProt Synonym Gene Names
V1aR
UniProt Entry Name
V1AR_RAT
NCBI Protein Information
vasopressin V1a receptor; antidiuretic hormone receptor 1a; arginine vasopressin receptor V1a; vascular/hepatic-type arginine vasopressin receptor

NCBI Summary for Avpr1a

This gene encodes a receptor for arginine vasopressin, a neurohypophyseal hormone involved in diuresis inhibition, smooth muscle contraction, liver glycogenolysis stimulation and regulation of adrenocorticotropic hormone release from the pituitary. This receptor represents one of three G protein-coupled arginine vasopressin receptors which functions through a phosphotidylinositol-calcium second messenger system in vascular and hepatic tissues. [provided by RefSeq, Jul 2008]
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UniProt Comments for Avpr1a

AVPR1A: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.

Protein type: Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1

Cellular Component: cytoplasmic vesicle membrane; integral to plasma membrane; integral to membrane; plasma membrane; cytoplasmic vesicle

Molecular Function: V1A vasopressin receptor binding; peptide hormone binding; vasopressin receptor activity

Biological Process: positive regulation of glutamate secretion; positive regulation of cellular pH reduction; positive regulation of systemic arterial blood pressure; cellular response to water deprivation; positive regulation of glycogen catabolic process; response to organic substance; elevation of cytosolic calcium ion concentration; positive regulation of cell proliferation; response to corticosterone stimulus; penile erection; positive regulation of prostaglandin biosynthetic process; grooming behavior; response to inorganic substance; maternal behavior; calcium-mediated signaling; myotube differentiation; positive regulation of heart rate; social behavior; positive regulation of cell growth; cellular response to hormone stimulus; negative regulation of female receptivity; G-protein coupled receptor protein signaling pathway; telencephalon development; regulation of systemic arterial blood pressure by vasopressin; negative regulation of transmission of nerve impulse; regulation of adrenocorticotropin hormone secretion; positive regulation of vasoconstriction; sperm ejaculation; positive regulation of blood pressure
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Research Articles on Avpr1a

1. Mice lacking V1a receptors have less secondary brain damage following experimental traumatic brain injury.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-Avpr1a antibody

 Products by Pathway  Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram

Diseases associated with anti-Avpr1a antibody

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >829 publications with Avpr1a and Cardiovascular Diseases
 Kidney Diseases Antibodies  >544 publications with Avpr1a and Kidney Diseases
 Hypertension Antibodies  >543 publications with Avpr1a and Hypertension
 Brain Diseases Antibodies  >348 publications with Avpr1a and Brain Diseases
 Hypotension Antibodies  >185 publications with Avpr1a and Hypotension
 Liver Diseases Antibodies  >122 publications with Avpr1a and Liver Diseases
 Edema Antibodies  >121 publications with Avpr1a and Edema
 Liver Cirrhosis Antibodies  >109 publications with Avpr1a and Liver Cirrhosis
 Inflammation Antibodies  >108 publications with Avpr1a and Inflammation
 Bradycardia Antibodies  >94 publications with Avpr1a and Bradycardia

Organs/Tissues associated with anti-Avpr1a antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >1518 publications with Avpr1a and Kidney
 Liver Antibodies  >549 publications with Avpr1a and Liver
 Embryonic Tissue Antibodies  >48 publications with Avpr1a and Embryonic Tissue
 Uncharacterized Tissue Antibodies  >1 publications with Avpr1a and Uncharacterized Tissue
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