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Vacuole Membrane Protein 1 (VMP1) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS566139

VMP1 is a transmembrane protein that co-localizes with LC3, a marker of the autophagosomes. It interacts with beclin-1, a mammalian autophagy initiator, through the VMP1-Atg domain, which is essential for autophagosome formation. VMP1 endogenous expression… More details

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Sample Manual Insert View PDF
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Product Overview

Product Name
Vacuole membrane protein 1 (VMP1), Polyclonal Antibody
Full Product Name
Vacuole membrane protein 1 polyclonal antibody
Product Gene Name
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Does react Ovalbumin
Form/Format
Liquid. Purified serum containing 0.2% sodium azide
Preparation and Storage
For long term storage, store at -20 degree C. Avoid freeze/thaw cycles
Shipping: Shipped on Blue Ice
Molecular Weight
24,148 Da
OMIM
611753
3D Structure
ModBase 3D Structure for Q96GC9
Immunogen
Synthetic peptide corresponding to aa 386-406 of human vacuole membrane protein 1 (VMP1)
Applications Tested/Suitable for anti-VMP1 antibody
Immunocytochemistry (ICC), Immunoprecipitation (IP), Western Blot (WB)

Other Notes

Small volumes of anti-VMP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for VMP1 purchase

MBS566139 is an antibody targeting VMP1. Also known as Vacuole membrane protein 1 polyclonal antibody. Reactive in Human, Mouse, Rat
Does react Ovalbumin. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for VMP1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
vacuole membrane protein 1 isoform 1
NCBI Official Synonym Full Names
vacuole membrane protein 1
NCBI Official Symbol
VMP1
NCBI Official Synonym Symbols
EPG3; TANGO5; TMEM49
UniProt Protein Name
Vacuole membrane protein 1
UniProt Synonym Protein Names
Transmembrane protein 49
UniProt Gene Name
VMP1
UniProt Synonym Gene Names
TDC1; TMEM49
NCBI Protein Information
vacuole membrane protein 1

NCBI Summary for VMP1

This gene encodes a transmembrane protein that plays a key regulatory role in the process of autophagy. The ectopic overexpression of the encoded protein in cultured cells triggers autophagy even under nutrient-rich conditions. This gene is overexpressed in pancreatitis affected acinar cells where the encoded protein mediates sequestration and degradation of potentially deleterious activated zymogen granules in a process termed, zymophagy. [provided by RefSeq, Jul 2016]
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UniProt Comments for VMP1

Stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis. Plays a role in the initial stages of the autophagic process through its interaction with BECN1 (). Involved in cell-cell adhesion. Plays an essential role in formation of cell junctions.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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