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Convulxin (CVX-alpha) Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS566186

Heterodimeric C-type lectin. Activates mammalian platelets via binding and clustering of p62/GPVI-receptors under physiological conditions. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Convulxin (CVX-alpha), Active Protein
Full Product Name
Convulxin
Product Gene Name
Form/Format
Lyophilized
Purity/Purification
Partially purified by multi-step chromatography
Preparation and Storage
For long term storage, store at -20 degree C
Stock solutions are stable for 8 hours at 20 degree C, for 2 days at 4 degree C or for 1 month when stored at -80 degree C
Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -80 degree C
Molecular Weight
18,141 Da
3D Structure
ModBase 3D Structure for O93426
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Source Note
Isolated from Crotalus durissus terrificus snake venom
Activity
<50ng/ml (minimal concentration to induce maximum activation of washed human platelets)
Reconstitution
Reconstitute in 10mM HEPES buffer, pH7.2. (We recommend adding a carrier protein such as BSA to the reconstitution buffer and any subsequent dilution buffers to prevent absorption on plastic surfaces.)
Solubility
Soluble in organic buffer (HEPES)
CAS Number
37206-04-5
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.

Other Notes

Small volumes of CVX-alpha active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CVX-alpha purchase

MBS566186 is an active protein targeting CVX-alpha. Also known as Convulxin.

Additional Details

NCBI/Uniprot data below describe general gene information for CVX-alpha. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
UniProt Primary Accession #
NCBI Official Full Name
Snaclec convulxin subunit alpha
UniProt Protein Name
Snaclec convulxin subunit alpha
Protein Family
UniProt Gene Name
CVX-alpha
UniProt Synonym Gene Names
CVX-alpha

UniProt Comments for CVX-alpha

Snake venom lectin that activates platelets by binding to the platelet collagen receptor glycoprotein VI (GP6) (PubMed:9153205). The indirect activation of integrin alpha-IIb/beta-3 (ITGA2B/ITGB3) also induced by the toxin is upstream the cytoskeletal translocation of GPIb, FcRgamma (FCER1G) and 14-3-3zeta (YWHAZ)(PubMed:16102113).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CVX-alpha active protein

 Reference Product  PubMed Publications
 FLNA active protein  >12 publications with CVX-alpha and FLNA
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