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P-Glycoprotein (ABCB1) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS566271

MBS566271 is an antibody targeting ABCB1. Also known as P-glycoprotein (human) monoclonal antibody (JSB-1). Reactive in Human, Chinese hamsterDoes not cross-react with mouse, rat or guinea pig P-glycoprotein. Host: Mouse. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
P-glycoprotein (ABCB1), Monoclonal Antibody
Full Product Name
P-glycoprotein (human) monoclonal antibody (JSB-1)
Product Gene Name
Clonality
Monoclonal
Isotype
IgG1
Clone Number
JSB-1
Host
Mouse
Species Reactivity
Human, Chinese hamster
Does not cross-react with mouse, rat or guinea pig P-glycoprotein
Form/Format
Liquid. In serum free culture supernatant containing 0.7% BSA and 0.1% sodium azide
Specificity
Recognizes a highly conserved cytoplasmic epitope of the human P-glycoprotein, the expression of which is strongly correlated with the degree of MDR derived MDR cell lines and human MDR cell lines from lung, ovaries and B cell lymphoma
Preparation and Storage
For long term storage, store at -20 degree C. Avoid freeze/thaw cycles
Shipping: Shipped on Blue Ice
Molecular Weight
141kDa
Chromosome Location
Chromosome: 7; NC_000007.13 (87133179..87342639, complement). Location: 7q21.12
OMIM
120080
3D Structure
ModBase 3D Structure for P08183
Immunogen
MDR (multidrug resistant)  Chinese hamster ovary cells (ChrC5)
Applications Tested/Suitable for anti-ABCB1 antibody
Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Frozen, Immunohistochemistry (IHC) Paraffin
Application Notes for anti-ABCB1 antibody
FC/FACS: 1:10
ICC: 1:20, acetone fixed cells
IHC-F/IHC-P: 1:20

Other Notes

Small volumes of anti-ABCB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ABCB1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
multidrug resistance protein 1
NCBI Official Synonym Full Names
ATP-binding cassette, sub-family B (MDR/TAP), member 1
NCBI Official Symbol
ABCB1
NCBI Official Synonym Symbols
CLCS; MDR1; P-GP; PGY1; ABC20; CD243; GP170
UniProt Protein Name
Multidrug resistance protein 1
UniProt Synonym Protein Names
ATP-binding cassette sub-family B member 1; P-glycoprotein 1
UniProt Gene Name
ABCB1
UniProt Synonym Gene Names
MDR1; PGY1
UniProt Entry Name
MDR1_HUMAN
NCBI Protein Information
multidrug resistance protein 1; P-glycoprotein 1; colchicin sensitivity; doxorubicin resistance

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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