Mouse Anti-IP6K2 Monoclonal Antibody – Cat# MBS566369

IP6K2 Antibody – Mouse Monoclonal

Name: IP6K2 Antibody; Monoclonal; Mouse; Human/Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS566369
Price: 555 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS566369

Inositol hexakisphosphate kinase-2 (IP6K2), generates the inositol pyrophosphate, diphosphoinositol pentakisphosphate (IP7), influencing apoptotic cell death. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

IP6K2, Monoclonal Antibody

Full Product Name

IP6K2 monoclonal antibody (4F10)

Product Gene Name

anti-IP6K2 antibody

Clonality

Monoclonal

Isotype

IgG1

Clone Number

4F10

Host

Mouse

Species Reactivity

Human, Mouse

Form/Format

Liquid. In PBS, pH7.4, containing 50% glycerol and 0.09% sodium azide

Purity/Purification

Protein G affinity purified

Preparation and Storage

For long term storage, store at -20 degree C
Shipping: Shipped on Blue Ice

Molecular Weight

49,186 Da

Chromosome Location

Chromosome: 3; NC_000003.11 (48725436..48754711, complement). Location: 3p21.31

OMIM

606992

3D Structure

ModBase 3D Structure for Q9UHH9

Source Note

Purified from hybridoma tissue culture supernatant

Immunogen

Recombinant human IP6K2 (inositol hexakisphosphate kinase 2)

Product Categories/Family for anti-IP6K2 antibody

Cellular Analysis; Cell Signaling

Applications Tested/Suitable for anti-IP6K2 antibody

Western Blot (WB)

Other Notes

Small volumes of anti-IP6K2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IP6K2 purchase

MBS566369 is an antibody targeting IP6K2. Also known as IP6K2 monoclonal antibody (4F10). Reactive in Human, Mouse. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for IP6K2. It may not necessarily be applicable to this product.

NCBI GI #

55769520

NCBI GeneID

51447

NCBI Accession #

NP_001005909.1

UniProt Primary Accession #

Q9UHH9

UniProt Secondary Accession #

Q6P0N8; Q9BSZ6; Q9BUW3; Q9H4P7; Q9NT63; Q9UFU6; A8K3B1; B4E3G6; G8JLL6

UniProt Related Accession #

Q9UHH9

GenBank Nucleotide #

NM_001005909.2

NCBI Official Full Name

inositol hexakisphosphate kinase 2 isoform a

NCBI Official Synonym Full Names

inositol hexakisphosphate kinase 2

NCBI Official Symbol

IP6K2

NCBI Official Synonym Symbols

PIUS; IHPK2

UniProt Protein Name

Inositol hexakisphosphate kinase 2

UniProt Synonym Protein Names

P(i)-uptake stimulator

Protein Family

Inositol hexakisphosphate kinase

UniProt Gene Name

IP6K2

UniProt Synonym Gene Names

IHPK2; InsP6 kinase 2; PiUS

UniProt Entry Name

IP6K2_HUMAN

NCBI Protein Information

inositol hexakisphosphate kinase 2; insp6 kinase 2; pi uptake stimulator; inositol hexaphosphate kinase 2; ATP:1D-myo-inositol-hexakisphosphate phosphotransferase

NCBI Summary for IP6K2

This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

UniProt Comments for IP6K2

IHPK2: Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Belongs to the inositol phosphokinase (IPK) family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; EC 2.7.4.21; Kinase, other

Chromosomal Location of Human Ortholog: 3p21.31

Cellular Component: nucleoplasm; intermediate filament cytoskeleton; nucleus

Molecular Function: inositol hexakisphosphate 5-kinase activity; inositol trisphosphate 3-kinase activity; ATP binding

Biological Process: inositol phosphate metabolic process; phosphate transport; positive regulation of apoptosis; phosphoinositide phosphorylation; cytokine and chemokine mediated signaling pathway; negative regulation of cell growth

Research Articles on IP6K2

1. Genetic polymorphisms in IP6K2 gene is associated with autoimmune disease.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-IP6K2 antibody

Products by Pathway	Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Inositol Phosphate Metabolism Pathway antibodies	Inositol Phosphate Metabolism Pathway Diagram
Interferon Signaling Pathway antibodies	Interferon Signaling Pathway Diagram
Interferon Alpha/beta Signaling Pathway antibodies	Interferon Alpha/beta Signaling Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Synthesis Of IPs In The Nucleus Pathway antibodies	Synthesis Of IPs In The Nucleus Pathway Diagram
Inositol Pyrophosphates Biosynthesis Pathway antibodies	Inositol Pyrophosphates Biosynthesis Pathway Diagram
Inositol Pyrophosphates Biosynthesis Pathway antibodies	Inositol Pyrophosphates Biosynthesis Pathway Diagram
Superpathway Of Inositol Phosphate Compounds antibodies	Superpathway Of Inositol Phosphate Compounds Diagram

Diseases associated with anti-IP6K2 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>7 publications with IP6K2 and Neoplasms
Carcinoma Antibodies	>3 publications with IP6K2 and Carcinoma
Ovarian Diseases Antibodies	>2 publications with IP6K2 and Ovarian Diseases
Ovarian Neoplasms Antibodies	>2 publications with IP6K2 and Ovarian Neoplasms
Cell Transformation, Neoplastic Antibodies	>1 publications with IP6K2 and Cell Transformation, Neoplastic
Necrosis Antibodies	>1 publications with IP6K2 and Necrosis

Organs/Tissues associated with anti-IP6K2 antibody

Organ/Tissue Name	Pubmed Publications
Esophagus Antibodies	>1 publications with IP6K2 and Esophagus
Mouth Antibodies	>1 publications with IP6K2 and Mouth
Blood Antibodies	>1 publications with IP6K2 and Blood
Pancreas Antibodies	>1 publications with IP6K2 and Pancreas
Embryonic Tissue Antibodies	>1 publications with IP6K2 and Embryonic Tissue
Uncharacterized Tissue Antibodies	>1 publications with IP6K2 and Uncharacterized Tissue