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Diphtheria Toxin Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS324187

MBS324187 is an antibody targeting Diphtheria toxin. Host: Goat. More details

$415 / 1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Diphtheria toxin, Polyclonal Antibody
Full Product Name
Diphtheria toxin
Product Synonym Names
Diphtheria toxin Antiserum Products
Clonality
Polyclonal
Isotype
Purified IgG fraction
Host
Goat
Form/Format
0.01M Phosphate Buffered Saline, pH 7.2, containing 0.1% sodium azide
Purity/Purification
>95%
Concentration
5.0 mg/ml (lot specific)
Specificity
Purified diphtheria toxin/toxoid
Preparation and Storage
Short term store at 2-8°C
Long term store at -20°C
Avoid freeze-thaws
3D Structure
ModBase 3D Structure for P00588
Cross Reactivity
Demonstrated reactivity with purified toxin
Note
Centrifuge briefly to ensure full recovery of contents
Applications Tested/Suitable for anti-Diphtheria toxin antibody
ELISA (EIA)

Other Notes

Small volumes of anti-Diphtheria toxin antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Diphtheria toxin. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
UniProt Primary Accession #
GenBank Nucleotide #
NCBI Official Full Name
Diphtheria toxin
UniProt Protein Name
Diphtheria toxin
UniProt Synonym Protein Names
NAD(+)--diphthamide ADP-ribosyltransferase
Protein Family
UniProt Entry Name
DTX_CORBE

UniProt Comments for Diphtheria toxin

Function: Diphtheria toxin, produced by a phage infecting Corynebacterium diphtheriae, is a proenzyme that, after activation, catalyzes the covalent attachment of the ADP ribose moiety of NAD to eukaryotic elongation factor 2 (eEF-2). Fragment A is the catalytic portion responsible for enzymatic ADP-ribosylation of elongation factor 2, while fragment B is responsible for binding of toxin to cell receptors and entry of fragment A. Ref.5 Ref.6

Catalytic activity: NAD+ + peptide diphthamide = nicotinamide + peptide N-(ADP-D-ribosyl)diphthamide.

Enzyme regulation: Partially inhibited by 1,8-naphthalimide (NAP). Ref.6

Subunit structure: Homodimer.

Sequence caution: The sequence AAA32182.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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