Cytokeratin 13 (KRT13) Antibody – Mouse Monoclonal

CytokeRatins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in Human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8. The individual Human cytokeRatins are numbered 1 to 20. The various epithelia in the Human body usually express cytokeRatins which are not only characteristic of the type of epithelium, but also related to the degree of matuRation or differentiation within an epithelium. CytokeRatin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeRatin antibodies are not only of assistance in the differential identification of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.

Dallenbach-Hellweg, G., Lang, G. (1991). Immunohistochemical studies on uterine tumors, Path. Res. Pract. 187, 36-43. Dockhorn-Dworniczak, B., Franke, W.W., Schröder, S., Czernobilsky, B., Gould, V.E. and Böcker, W. (1987). Patterns of expression of cytoskeletal proteins in Human thyroid gland and thyroid carcinomas, Differentiation 35, 53-71. Franke, W.W., Moll, R., Achtstätter Th. and Kuhn, C. (1986) Cell typing of epithelia and carcinomas of the female genital tract using cytoskeletal proteins as markers, Banbury Report 21, Viral Etiology of Cervical Cancer, Cold Spring Harbor LaboRatory (NY), 121-148. Moll, R., Achtstätter, Th., Becht, E., Balcarova-Ständer, J., Ittensohn, M. and Franke, W.W. (1988). CytokeRatins in normal and malignant transitional epithelium, Am. J. Pathol. 132, 123-144. Moll, R., Franke, W.W., Schiller, D.L., Geiger, B. and Krepler, R. (1982). The Catalog of Human cytokeRatins: Patterns of expression in normal epithelia, tumors and cultured cells, Cell 31, 11-24. Demirkesen, C., Hoede, N., Moll, R. (1995). Epithelial markers and differentiation in adnexal neoplasms of the skin: an immunohistochemical study including individual cytokeRatins, J Cutan Pathol 22: 518-535.

Small volumes of anti-KRT13 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS570160 is an antibody targeting KRT13. Also known as Mouse anti CytokeRatin 13. Reactive in Bovine, Human, Rat. Host: Mouse.