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AFN-1252 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750001

Description: AFN-1252 (Debio 1452) is a potent inhibitor of enoyl-acyl carrier protein reductase (FabI), inhibited all clinical isolates of Staphylococcus aureus and Staphylococcus epidermidis at concentrations of More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AFN-1252, Inhibitor
Full Product Name
AFN-1252
Product Gene Name
AFN-1252, inhibitor
Form/Format
POWDER
Purity/Purification
98.7%
Preparation and Storage
Store at 0 to 4°C for short term (days to weeks) or -20°C for long term (months)
Molecular Weight
375.42
CAS
620175-39-5
Formula
C22H21N3O3
Smiles
CN(Cc1oc2ccccc2c1C)C(=O)\C=C\c1cnc2NC(=O)CCc2c1
Targets (IC50)
enoyl-acyl carrier protein reductase (FabI): None
Solubility
DMSO: 5.8 mg/mL
(< 1mg/mL refers to the product slightly soluble or insoluble)
1H NMR Spectrum
Consistent with structure
LCMS
Consistent with structure
Conclusion
The test result is consistent with structure

Product Categories/Family for AFN-1252, inhibitor

Immunology

Testing Data (TD) of AFN-1252, inhibitor

AFN-1252 Inhibitor – Cat# MBS5750001

Chemical Structure of AFN-1252, inhibitor

AFN-1252 Inhibitor, Chemical Structure – Cat# MBS5750001

Product References and Citations for AFN-1252, inhibitor

1. Karlowsky JA, et al. AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. Antimicrob Agents Chemother. 2009 Aug; 53 (8):3544-8.

Other Notes

Small volumes of AFN-1252, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AFN-1252 purchase

MBS5750001 is an inhibitor targeting AFN-1252.
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