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Delpazolid Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750029

MBS5750029 is an inhibitor targeting Delpazolid. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Delpazolid, Inhibitor
Full Product Name
Delpazolid
Form/Format
POWDER
Purity/Purification
99.6%
Preparation and Storage
For 3 years at -20 degree C (powder)
For 2 years -80 degree C in solvent.
Molecular Weight
308.313
CAS
1219707-39-7
Formula
C14H17FN4O3
Smiles
O=C1O[C@@H](CO)CN1c1ccc(N2C=NN(C)CC2)c(F)c1
Bioactivity
Delpazolid, also known as LCB01-0371, is a new oxazolidinone with cyclic amidrazone. In vitro activity of LCB01-0371 against 624 clinical isolates was evaluated and compared with those of linezolid, vancomycin, and other antibiotics. LCB01-0371 showed good activity against Gram-positive pathogens. In vivo activity of LCB01-0371 against systemic infections in mice was also evaluated. LCB01-0371 was more active than linezolid against these systemic infections. LCB01-0371 showed bacteriostatic activity against Staphylococcus aureus.
Solubility Note
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Structure of Delpazolid, inhibitor

Delpazolid Inhibitor – Cat# MBS5750029

Product References and Citations for Delpazolid, inhibitor

1. Jeong JW, et al. In vitro and in vivo activities of LCB01-0371, a new oxazolidinone.Antimicrob Agents Chemother. 2010 Dec; 54 (12):5359-62.

Other Notes

Small volumes of Delpazolid, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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