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NVP-AAM077 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750034

PEAQX(NVP-AAM 077) is an effective and orally available NMDA antagonist. It can inhibit human NMDA receptors for 1A/2A(IC50: 270 nM), rather than 1A/2B(29,600 nM). More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NVP-AAM077, Inhibitor
Full Product Name
NVP-AAM077
Product Gene Name
Form/Format
POWDER
Purity/Purification
98.0%
Preparation and Storage
3 years -20°C powder
Molecular Weight
454.20
CAS
459836-30-7
Molecular Formula
C17H17BrN3O5P
Receptor
hNMDA 1A/2A receptors
270nM
Bioactivity
PEAQX (NVP-AAM 077) is a potent and orally active NMDA antagonist with a 15-fold preference for human NMDA receptors with the 1A/2A (IC50=270 nM), rather than 1A/2B (29,600 nM).
Solubility
DMSO
10 mM ( > 1 mg/ml refers to the product slightly soluble or insoluble)
HNMR
Consistent with structure
HPLC
Consistent with structure

Product References and Citations for NVP-AAM077, inhibitor

1. Auberson YP, et al. 5-Phosphonomethylquinoxalinediones as competitive NMDA receptor antagonists with a preference for the human 1A/2A, rather than 1A/2B receptor composition. Bioorg Med Chem Lett. 2002 Apr 8; 12 (7):1099-102.

Other Notes

Small volumes of NVP-AAM077, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NVP-AAM077 purchase

MBS5750034 is an inhibitor targeting NVP-AAM077.
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