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Desmethyl-VS-5584 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750062

MBS5750062 is an inhibitor targeting Desmethyl-VS-5584. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Desmethyl-VS-5584, Inhibitor
Full Product Name
Desmethyl-VS-5584
Form/Format
POWDER
Purity/Purification
98.9%
Preparation and Storage
For 3 years at -20 degree C (powder)
For 2 years -80 degree C in solvent.
Molecular Weight
340.391
CAS
1246535-95-4
Formula
C16H20N8O
Pathways
PI3K/Akt/mTOR signaling
Smiles
Nc1ncc(c2c3ncn(C(C)C)c3nc(N3CCOCC3)n2)cn1
Receptor
mTOR; PI3K
Bioactivity
Desmethyl-VS-5584 is a demethyl analogue of VS-5584, which is a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer.
Solubility Note
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Structure of Desmethyl-VS-5584, inhibitor

Desmethyl-VS-5584 Inhibitor – Cat# MBS5750062

Product References and Citations for Desmethyl-VS-5584, inhibitor

1. Shao Z,et al. VS-5584, a Novel PI3K-mTOR Dual Inhibitor, Inhibits Melanoma Cell Growth In Vitro and In Vivo. PLoS One. 2015 Jul 23; 10 (7).

Other Notes

Small volumes of Desmethyl-VS-5584, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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