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Nolatrexed Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750090

MBS5750090 is an inhibitor targeting Nolatrexed. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Nolatrexed, Inhibitor
Full Product Name
Nolatrexed
Form/Format
POWDER
Purity/Purification
97.9%
Preparation and Storage
For 3 years at -20 degree C (powder)
For 2 years -80 degree C in solvent.
Molecular Weight
284.33
CAS
147149-76-6
Formula
C14H12N4OS
Pathways
DNA Damage/DNA Repair
Smiles
Cc1ccc2nc(N)[nH]c(=O)c2c1Sc1ccncc1
Receptor
Thymidylate synthase
Bioactivity
Nolatrexed, also known as AG337, is a thymidylate synthase inhibitor with potential anticancer activity.
Solubility Note
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Product Categories/Family for Nolatrexed, inhibitor

Cancer

Product References and Citations for Nolatrexed, inhibitor

1. Zheng J, et al. Metastatic nasopharyngeal carcinoma outcomes in patients on cisplatin with nolatrexed or 5-fluorouracil. Oncol Res Treat. 2014; 37 (10):540-4. doi: 10.1159/000368107. Epub 2014 Sep 16. PubMed PMID: 25342504.

Other Notes

Small volumes of Nolatrexed, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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